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. 2023 Jul 10;8(13):e164947. doi: 10.1172/jci.insight.164947

Figure 5. MYC represses Csf1 expression through regulation of miR-17/20a.

Figure 5

(A) qPCR for miR-17-5p and -20a-5p expression in Myc-knockin tumors and p53-driven GEMM tumor sample (n = 3). (B) qPCR for miR-17-5p and -20a-5p expression after Myc siRNA treatment compared with the Scr (siScr) control (n = 3). (C) miR-17-5p and -20a-5p expression after dTAG-v1 treatment (n = 3). (D) Csf1 mRNA expression after miR17-5p and -20a inhibition treatment as compared with the negative inhibitor control (n = 3). (E) Csf1 mRNA expression after miR17-5p and -20a mimic treatment compared with the negative mimic control (n = 3). (*P < 0.05, **P < 0.01, ***P < 0.001.)