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. 2023 Jul 19;14(4):100740. doi: 10.1016/j.jaim.2023.100740

Table 5.

Pharmacological action of ingredients of Rajanyadi Churna

Sr. no. Name of ingredient Action
1. Rajani
Curcuma longa L.
  • An evidence-based study reported that curcumin improves nasal airflow and modulates the immune response in patients of AR. It subsides the symptoms like sneezing, and rhinorrhea, along with nasal congestion through reduction of nasal airflow resistance [18].

  • Curcumin also has antioxidant properties and demonstrated to reduce the oxidative stress that occurs in allergic rhinitis giving relief in symptoms [19].

2. Darvi
Cedrus deodara Roxb.
  • Possesses significant anti-allergic activity demonstrated in experimental rat models [20].

3. Saral
Pinus roxburghii Sarg.
  • The anti-allergic and anti-asthmatic activities of the plant extract were demonstrated in animal models showing significant results [21].

  • The plant also possesses anti-inflammatory and analgesic properties [22].

4. Pippali
Piper longum L.
  • The increased production of nitric oxide was observed in AR. Eosinophils are the measurable source of nitric oxide. The experimental model of AR demonstrated a significant reduction in the level of nitric oxide resulting in the anti-allergic effect of piperine [23].

5. Bruhti (Laghu)
Solanum surattense L.
  • Possesses anti-inflammatory, antioxidant, and antihistaminic properties [24].

6. Bruhti (Kantakari)
Solanum indicum L.
  • Possesses anti-inflammatory, antioxidant, immunomodulatory, appetizer, and anti-asthmatic properties [24].

7. Prishnaparni
Uraria picta DC.
  • Anti-inflammatory potential and works on respiratory diseases [25].

8. Shatavha
Anethum sowa Roxb.
  • Possesses biological activities including antioxidant, antiviral, antibacterial, analgesic and anti-inflammatory, cytotoxic properties [26].