Table 2.
Effects of different treatments on blood routine exam of mice(mean ± SD, n = 10).
| Group | Normal | Model | 5-FU | TPA-L+5-FU | TPA-M+5-FU | TPA-H+5-FU |
|---|---|---|---|---|---|---|
| WBC( × 109/L) | 6.61 ± 2.58*** | 13.22 ± 3.23 | 4.71 ± 0.99*** | 4.77 ± 0.60*** | 5.31 ± 0.93*** | 5.16 ± 0.96*** |
| LYM(%) | 80.29 ± 4.17*** | 54.82 ± 6.35 | 62.65 ± 11.25 | 72.45 ± 11.29*** | 69.70 ± 7.27*** | 62.94 ± 7.26* |
| NEU(%) | 17.47 ± 4.08*** | 39.43 ± 6.90 | 32.14 ± 9.61 | 23.15 ± 9.66*** | 26.03 ± 7.31*** | 32.74 ± 6.33* |
| MONO(%) | 0.87 ± 0.43*** | 4.98 ± 1.57 | 4.22 ± 2.22 | 3.66 ± 2.01 | 3.40 ± 1.11* | 3.34 ± 1.63* |
| EOS(%) | 1.34 ± 0.45** | 0.74 ± 0.19 | 0.99 ± 0.51 | 0.72 ± 0.52 | 0.87 ± 0.37 | 0.96 ± 0.50 |
| BASO(%) | 0.030 ± 0.067 | 0.030 ± 0.048 | 0.000 ± 0.000 | 0.020 ± 0.063 | 0.000 ± 0.000### | 0.020 ± 0.042 |
| RBC( × 1012/L) | 10.34 ± 0.46*** | 9.03 ± 0.37 | 8.82 ± 0.44 | 8.71 ± 0.36* | 8.60 ± 0.35* | 8.60 ± 0.34 |
| HGB(g/L) | 158.9 ± 6.7*** | 136.2 ± 6.2 | 134.7 ± 5.6 | 130.1 ± 4.7* | 131.0 ± 5.1 | 133.8 ± 5.1 |
| HCT(%) | 44.9 ± 1.68*** | 39.1 ± 1.27 | 38.5 ± 1.60 | 37.1 ± 1.15**# | 37.2 ± 1.18** | 38.2 ± 1.28 |
| PLT( × 109/L) | 1312.3 ± 149.9*** | 1740.9 ± 169.8 | 1601.5 ± 196.8 | 1767.0 ± 116.1# | 1657.0 ± 162.9 | 1783.9 ± 146.7# |
Note: *p < 0.05, **p < 0.01 and ***p < 0.001 compared with model group; #p < 0.05 and ###p < 0.001 compared with 5-FU group.