Table 2.

Geometric mean opsonisation index pre-4-weeks and 4-weeks post-12-month dose of PCV

	Pre-12-month PCV			Post-12-month PCV
	0+1 PCV10*	1+1 PCV10	1+1 PCV13	0+1 PCV10	0+1 PCV13	1+1 PCV10	1+1 PCV13
PCV10 serotypes
1	4 (4–5)	8 (6–10)	5 (4–6)	26 (17–40)	74 (44–123)	350 (224–548)	840 (575–1227)
4	4 (4–5)	8 (6–11)	8 (5–13)	463 (245–877)	1439 (936–2213)	2246 (1641–3075)	5140 (3952–6687)
5	4 (4–4)	15 (11–22)	11 (8–16)	21 (16–29)	73 (44–122)	782 (576–1061)	1688 (1250–2280)
6B	6 (4–9)	18 (10–31)	4 (4–5)	42 (19–92)	414 (179–955)	1519 (1101–2095)	3889 (2267–6672)
7F	9 (5–15)	219 (126–381)	317 (179–561)	1605 (1008–2557)	4227 (2739–6524)	2340 (1718–3189)	6534 (5354–7974)
9V	6 (4–8)	49 (28–86)	17 (9–32)	813 (426–1549)	3732 (2455–5675)	3000 (2283–3941)	9582 (7612–12 062)
14	28 (13–62)	160 (75–345)	173 (82–366)	3016 (1851–4914)	6672 (4389–10 141)	4176 (2729–6389)	15 081 (11 147–20 403)
18C	4 (4–4)	9 (7–13)	8 (6–11)	3889 (2422–6243)	1915 (1220–3005)	6194 (4489–8548)	3465 (2735–4390)
19F	5 (4–6)	65 (35–118)	13 (9–19)	1032 (579–1837)	800 (443–1447)	6120 (4678–8006)	6192 (4802–7986)
23F	6 (4–9)	13 (8–21)	9 (5–16)	133 (58–305)	1250 (610–2562)	1049 (636–1731)	5884 (4213–8217)
Additional PCV13 serotypes
3	8 (6–10)	8 (6–10)	23 (16–35)	8 (6–11)	357 (250–510)	8 (6–12)	815 (628–1057)
6A	6 (4–9)	9 (5–14)	8 (5–13)	53 (22–125)	1809 (952–3438)	171 (76–388)	9540 (7002–12 998)
19A	6 (5–7)	9 (6–13)	9 (7–13)	93 (59–145)	663 (440–1001)	215 (128–361)	3167 (2332–4301)

Data are geometric means (95% CI). PCV=pneumococcal conjugate vaccine. PCV10=10-valent PCV. PCV13=13-valent PCV.

^*Pre-12-month PCV opsonophagocytic assays were only done in one of the two 0 + 1 groups, as these groups have the same vaccination status up to 12 months of age.