Table 5.

Case description of patients with ZCS and abnormal PET that changed clinical decision making

Symptoms	Risk factors	PET result	Clinical course
Male (in his 50 seconds), atypical AP	Severe dyslipidaemia (retrospectively)	No scar, antero-septo-apical ischemia (SDS 6)	Severe stenosis of mid LAD, PCI with 1 × DES
Male (in his 40 seconds ), atypical chest pain, significant risk factors	NIDDM, dyslipidaemia, AHT, former smoker	Non-transmural scar basal inferior (SRS 6) with large ischemia (SDS 9)	2 vessel CAD with CTO of mid RCA and severe stenosis M2. Elective PCI to both lesions
Female (in her 60 seconds), typical AP CCS II, SOB NYHA II, 2 weeks ago arm pain during several hours	Former smoker	Non-transmural scar antero-apical (SRS 3) with ischemia (SDS 7)	No follow-up data available, should have undergone angiogram
Male (in his 50 seconds), SOB NYHA II, LVEF 38% (TTE)	IDDM, dyslipidaemia, former smoker	Large anterior ischemia (SDS 20), predominantly in LAD with corresponding reduced myocardial blood flow during stress	Non-obstructive CAD in angiography, perfusion defect most likely due to microvascular dysfunction compatible with non-ischemic cardiomyopathy

AP, angina pectoris; CAD, coronary artery disease; CTO, chronic total occlusion; DES, drug eluting stent; LAD, left anterior descending; NIDDM, non-insulin dependent diabetes mellitus; PCI, percutaneous coronary intervention; SDS, summed difference score; SOB, shortness of breath; SRS, summed rest score