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. 2023 Jun 19;40(8):1807–1816. doi: 10.1007/s10815-023-02859-z

Table 2.

Subgroup analyses of TSC, SC, PR, and TM based on age, continent, income, and abstinence time

Outcomes Age (years) Continent Income Abstinence time (days)
18–29 30–39 Asia Europe North America Oceania High income Upper Middle income 2–3 2–4 2–7
TSC R2 0.91 0.77 0.79 0.57 0.73 0.48 0.93 0.71 0.99 1.00 0.90
Regression coefficient (95% CI) − 2.54 (− 2.75, − 2.32) − 2.54 (− 3.46, − 1.62) − 2.16 (− 2.43, − 1.89) − 2.72 (− 3.02, − 2.43) − 5.00 (− 6.74, − 3.27) 2.76 (1.34, 4.17) − 4.47 (− 4.74, − 4.20) − 1.58 (− 1.83, − 1.33) 2.04 (1.97, 2.12) 3.73 (3.69, 3.77) − 4.64 (− 5.00, − 4.31)
P value < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001
SC R2 0.87 0.70 0.94 0.98 0.88 / 0.96 0.66 0.78 1.00 0.69
Regression coefficient (95% CI) − 0.93 (− 0.97, − 0.81) − 0.73 (− 0.94, − 0.52) − 1.16 (− 1.21, − 1.10) − 0.80 (− 0.83, − 0.77) − 2.80 (− 3.32, − 2.27) / − 0.72 (− 0.75, − 0.68) − 0.99 (− 1.12, − 0.86) 0.38 (0.29, 0.46) − 2.69 (− 2.84, − 2.54) − 1.18 (− 1.32, − 1.05)
P value < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 / < 0.001 < 0.001 < 0.001 < 0.001 < 0.001
PR R2 0.92 0.95 0.54 0.14 0.44 / 0.33 0.38 0.74 / 0.26
Regression coefficient (95% CI) − 0.69 (− 0.74, − 0.64) − 0.66 (− 0.72, − 0.59) − 0.27 (− 0.32, − 0.22) 0.15 (− 0.01, 0.30) 0.31 (0.12, 0.50) / 0.59 (0.33, 0.85) − 0.26 (− 0.32, − 0.20) − 0.25 (− 0.34, − 0.16) / − 0.22 (− 0.28, − 0.15)
P value < 0.001 < 0.001 < 0.001 0.06 0.003 / < 0.001 < 0.001 < 0.001 / < 0.001
TM R2 0.77 0.69 0.94 0.97 / 1.00 0.64 0.77 / 0.80 0.14
Regression coefficient (95% CI) − 0.56 (− 0.66, − 0.46) − 0.61 (− 0.87, − 0.36) − 0.75 (− 0.80, − 0.70) − 0.45 (− 0.49, − 0.42) / 0.48 (0.48, 0.48) 0.43 (0.34, 0.52) − 0.43 (− 0.49, − 0.36) / 0.63 (0.48, 0.77) − 0.17 (− 0.27, − 0.07)
P value < 0.001 < 0.001 < 0.001 < 0.001 / < 0.001 < 0.001 < 0.001 / < 0.001 0.001

*Since the number of data points for the subgroups of age (40–45 year old), continent (Africa, South America), income (lower middle income, low income), and abstinence time (2–5 days, 2–6 days) were less than 10, they were not included in the subgroup analyses

/: No data