Table 2.
Patient no. | Age + sex | MAHA/TMA | Cycle onset no. | Schistocytes | Hb | Platelets | LDH | Retic | Haptoglobin Nadir | Bilirubin | Other | End organ damage | With infection | No. of episodes |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
15 | 84 M | MAHA | 2 | Yes | 88 | 87 | 338 | 303 | NA | 12 | - | Nil | - | 1 |
16 | 65 M | MAHA | 3 | Yes | 101 | 49 | 458 | 219 | NA | 10 | - | Nil | - | 1 |
21 | 56 M | MAHA (subTMA) | 7 | Yes | 90 | 47 | 380 | NA | NA | 7 | - | AKI Cr 86–140 | Influenza A | 1 |
29 | 64 F | MAHA | 4 | Yes | 120 | 76 | 310 | NA | NA | 9 | - | Nil | Rhinovirus | 1 |
30 | 72 M | MAHA | 4 | Yes | 94 | 89 | 269 | 245 | Undetectable | 12 | Urine haemosiderin | Nil | - | 2 |
36 | 81 F | MAHA (subTMA) | 7 | Yes | 108 | 123 | 257 | 192 | NA | 4 | - | AKI Cr 176–225 | - | 2 |
TMA | 12 | Yes | 66 | 120 | 313 | 164 | Undetectable | 7 | Low C3, normal C4 | Renal | - | |||
37 | 81 M | MAHA (subTMA) | 3 | Yes | 89 | 72 | 255 | NA | Low 0.2 | 8 | - | AKI Cr 111–138 | - | 2 |
38 | 70 F | MAHA (subTMA) | 5 | Yes | 92 | 66 | 417 | NA | NA | 4 | - | AKI Cr 90–117 | RSV | 2 |
TMA | 17 | Yes | 92 | 27 | 987 | 12 | Undetectable | 11 | - | Renal, Cardiac | Influenza A | |||
39 | 64 M | MAHA (subTMA) | 6 | Yes | 81 | 68 | 415 | NA | NA | 14 | - | AKI Cr 119–216 | - | 1 |
41 | 82 M | MAHA | 6 | Yes | 94 | 100 | 507 | 208 | NA | 11 | - | Nil | - | 2 |
44 | 77 M | MAHA | 7 | Yes | 101 | 58 | 344 | 91 | Low 0.48 | 6 | - | Nil | - | 1 |
Units and normal ranges—Haemoglobin (Hb) males 130–170 g/L and females 120–150 g/L, Platelets 150–400 × 109/L, LDH < 250 U/L, Reticulocyte count 50–100 × 109/L, Haptoglobin 0.5–2.6 g/L, Bilirubin < 20 µmol/L, Creatinine (Cr) males 60–110 µmol/L, females 45–90 µmol/L.
NA not available, sub TMA subclinical TMA (in bold).