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. 2023 Jul 26;13:12136. doi: 10.1038/s41598-023-39215-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The structure of the pipeline and different steps are shown. The method consist of data quality check data sorting by race, statistical analyses, feature selection and classification tests, pathway analysis and evaluation in gene expression and survival in TCGA cohort of selected genes associated to metabolites mapped.