Skip to main content
. 2023 Jul 26;14:4485. doi: 10.1038/s41467-023-40228-7

Fig. 1. Clinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.

Fig. 1

A, B Body weight variation over four days post-infection. C Lung weight measured at 4 dpi. D, E Clinical score over four days post-infection. The clinical score is based on a cumulative 0–4 scale: ruffled fur; slow movements; apathy; and absence of exploration activity. F Lung weight-to-body weight ratio measured at 4 dpi. A–F Horizontal lines indicate median and the interquartile range (n = 8/group). B, C, E, F Kruskal-Wallis test followed by the Dunn’s multiple comparisons test (the adjusted p value is indicated when significant). G, H Olfactory performance measured at 3 days post-infection (dpi). The olfaction test is based on the hidden (buried) food finding test. Curves represent the olfactory performance of animals during the test (G) and bars represent the final results (H) (n = 8/group). Chi-square test for trend (the adjusted p value is indicated when significant). See Supplementary Figs. 1, 2.