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. 2023 Jul 26;13:12091. doi: 10.1038/s41598-023-39259-3

Table 3.

Univariate analysis of prognostic factors affecting BCFI and OS, The Ruijin cohort.

Characteristics P value
BCFI OS
Age (< 40 vs. 40–49 vs.50–70 vs. > 70) 0.053 0.001
Menstrual status (Pre/Peri- vs. Post-) 0.335 0.016
Residence (Large metropolitan vs. Metropolitan vs. Urban vs. Rural) 0.596 0.875
CCI (0 vs. 1–2 vs. 3 +) 0.173 0.756
Education level (Post-graduated vs. Degree vs. High school vs. Middle school) 0.062 0.127
BMI (< 25 vs. 25–30 vs. ≥ 30) 0.389 0.220
Histology type (IDC vs. Non-IDC) 0.304 0.695
Tumor size (≤ 2.0 cm vs. > 2.0 cm)  < 0.001  < 0.001
ALN status (Negative vs. Positive)  < 0.001  < 0.001
Tumor stage (I vs. II vs. III)  < 0.001  < 0.001
Histological grade (I vs. II vs. III)  < 0.001 0.050
LVI (Negative vs. Positive)  < 0.001 0.003
ER (Negative vs. Positive)  < 0.001  < 0.001
PR (Negative vs. Positive)  < 0.001  < 0.001
HER2 (Negative vs. Positive) 0.089 0.987
Ki67 (< 14% vs. ≥ 14%)  < 0.001 0.001
Molecular subtype (HR + /HER2- vs. HER2 + vs. TNBC) 0.001 0.001
Chemotherapy (No vs. Yes) 0.001 0.912
Radiation therapy (No vs. Yes) 0.002 0.177
Time to surgery (≤ 1w vs. 1–2 w vs. > 2w) 0.088 0.002