Table 2.
Nasal cytology and immunohistochemistry findings, subdivided by low, medium and high CCG.
Entire population | Patients with low CCG, N = 10 (25.6%) | Patients with moderate CCG, N = 13 (33.3%) | Patients with high CCG, N = 16 (41.0%) | P value | |
---|---|---|---|---|---|
Nasal cytology findings | |||||
Patients with eosinophils, % | 46.2 | 100.0 | 46.2 | 12.5 | < 0.0001 |
Patients with mast cells, % | 5.1 | 0.0 | 7.7 | 6.3 | 0.685 |
Patients with eosinophils + mast cells, % | 48.7 | 0.0 | 46.2 | 81.3 | < 0.0001 |
Immunohistochemistry findings | |||||
Eosinophilis count, median (IQ 25–75) | 22 (7–45) | 15 (4–42) | 17 (4.5–38.5) | 30 (13.5–56.5) | 0.234 |
Mast cells count, median (IQ 25–75) | 11 (3–20) | 9 (8–11) | 6 (2.5–10.5) | 17.5 (11–33) | 0.018 |
Lamina propria mast cells count, median (IQ 25–75) | 7 (3–16) | 9 (3–11) | 4.5 (2–8) | 7 (4.5–18) | 0.202 |
Intraepithelial mast cells count, median (IQ 25–75) | 0 (4–9) | 0 (0–5) | 1 (0–4) | 9 (3.5–22) | < 0.0001 |
Mast cells presence, % | 97.4 | 90.0 | 100.0 | 100.0 | 0.226 |
Lamina propria mast cells presence, % | 97.4 | 90.0 | 100.0 | 100.0 | 0.226 |
Intraepithelial mast cells presence, % | 64.1 | 30.0 | 46.2 | 100.0 | < 0.0001 |
Intraepithelial mast cells ≥ lamina propria mast cells, % | 25.6 | 20.0 | 7.7 | 43.8 | 0.077 |
Significant are in value [bold].