Table 3.

TCD measurements at different timings within each group

Variables	Baseline	After 1hour	After 6hours	P value
Group M
MV (cm/s)	68.1 ± 7.09	66.4 ± 6.92	67.1 ± 7.05	0.373
DIAS (cm/s)	48.4 ± 5.42	46.9 ± 8.50	47.7 ± 6.32	0.470
PI	0.77 ± 0.04	0.66 ± 0.05*	0.66 ± 0.05	< 0.001
CPP (mmHg)	103.3 ± 12.7	87.8 ± 10.6*	89.8 ± 10.9	< 0.001
MCA Velocity (cm/s)	3.54 ± 0.44	3.47 ± 0.38	3.42 ± 0.30	0.285
Group L
MV (cm/s)	66.1 ± 6.52	63.3 ± 5.98	64.3 ± 6.78	0.154
DIAS (cm/s)	46.8 ± 3.52	43.5 ± 7.50	44.5 ± 6.81	0.113
PI	0.77 ± 0.05	0.67 ± 0.05*	0.67 ± 0.06	< 0.001
CPP (mmHg)	103.6 ± 12.6	86.2 ± 13.02*	83.7 ± 14.6	< 0.001
MCA Velocity (cm/s)	3.62 ± 0.44	3.51 ± 0.35	3.54 ± 0.36	0.371

Group M = Magnesium sulfate group, Group L = Labetalol group, n = Total number of subjects in each group, MV = Mean Velocity, DIAS = Mean End Diastolic Velocity, PI = Pulsatility Index, CPP = Cerebral Perfusion Pressure, MCA Velocity = Middle Cerebral Artery Velocity.

Data were expressed as mean ± SD.

Repeated measure ANOVA test

P < 0.05 is significant.

* Both PI and CPP were statistically high significantly lower in both groups after 1 and 6 hours of drug administration compared to the baseline measurement.