Table 2. Complications of immunosuppressive therapy with precursor-targeted immune-mediated anemia.
| Complication | Duration of immunosuppressive therapy at the time complication occurred (days) |
Dosage at the time of complication (mg/kg/day) |
Response for immunosuppressive therapy | Outcome |
|---|---|---|---|---|
| Aspiration pneumonia | 7 | Pre (2) and MMF (20) | NE | Died on the same day |
| Pancreatitis | 15 | Pre (2) and CyA (8.7) | NE | Died 13 days later |
| Pancreatitis | 22 | Pre (2.3) and CyA (11.5) | NE | Died 4 days later |
| Neurological disorder | 29 | Pre (1.9) and CyA (20) | NE | Died 6 days later |
| Pancreatitis | 74 | Pre (1.6) and MMF (14.8) | NE | Died the next day |
| Orbital abscess | 77 | Pre (1.4) and CyA (10) | NE | Survived |
| Pneumonia | 102 | Pre (1.4) and Lef (4.3) | NE | Died the next day |
| Hepatic abscess | 114 | Pre (1.4) and CyA (9.4) | Non-responder | Died the next day |
| Aspiration pneumonia | 116 | Pre (2) and MMF (26.8) | Responder | Died 10 days later |
| Pyothorax | 155 | Pre (0.2) and Lef (3.2) | Non-responder | Died the next day |
| Prostate abscess | 167 | Pre (1.2) and MMF (27) | Responder | Survived |
| Pancreatitis | 318 | Pre (2) and MMF (30.4) | Responder | Died 30 days later |
| Pyometra | 1,491 | MMF (12.5) | Responder | Survived |
CyA, cyclosporine; MMF, mycophenolate mofetil; Lef, leflunomide; Pre, prednisolone; NE, not evaluated.