Table 2.
Baseline Characteristics of Patients and the Clinical Background of the Third-generation and Non-third-generation Cephalosporin Treatment Groups after Propensity Score Matching.
Variable | Third-generation cephalosporins (n=53) |
Non-third-generation cephalosporins (n=53) |
p value | ||
---|---|---|---|---|---|
Age, ≥65 years; n (%) | 42 | (79.2) | 37 | (69.8) | 0.373a |
Sex, Male (%) | 36 | (67.9) | 38 | (71.7) | 0.833a |
Charlson Comorbidity Index; median (IQR) | 3.0 | (2.0-4.0) | 3.0 | (2.0-5.0) | 0.369b |
Disseminated intravascular coagulation; n (%) | 6 | (11.3) | 7 | (13.2) | 1.000a |
Anticancer agents or immunosuppressants; n (%) | 24 | (45.3) | 21 | (39.6) | 0.695a |
Source of Infection | |||||
Lower gastrointestinal tract or intra-abdominal; n (%) | 3 | (5.7) | 4 | (7.5) | 1.000a |
Biliary tract; n (%) | 21 | (39.6) | 22 | (41.5) | 1.000a |
Urinary tract; n (%) | 13 | (24.5) | 14 | (26.4) | 1.000a |
Respiratory system; n (%) | 3 | (5.7) | 0 | (0) | 0.243a |
Intravenous catheter; n (%) | 2 | (3.8) | 0 | (0) | 0.495a |
Unclear or others; n (%) | 11 | (20.8) | 13 | (24.5) | 0.817a |
Clinical characteristics | |||||
eGFR, mL/min/1.73 m2; median (IQR) | 55.0 | (36.0-70.0) | 59.0 | (42.3-73.7) | 0.774b |
WBC, /μL; median (IQR) | 7,600 | (4,300-9,800) | 8,500 | (4,700-11,500) | 0.822b |
CRP (≥15), mg/dL; n (%) | 5 | (9.4) | 6 | (11.3) | 1.000a |
Pitt Bacteremia Score (≥4 points); n (%) | 16 | (30.2) | 19 | (35.8) | 0.680a |
Implementation of source control; n (%) | 21 | (39.6) | 22 | (41.5) | 1.000a |
Duration of antimicrobial administration, days; median (IQR) | 13.0 | (9.0-16.0) | 13.0 | (9.0-15.0) | 0.869b |
Microorganisms | |||||
Enter obacter cloacae or Enterobacter cloacae complex; n (%) | 36 | (67.9) | 34 | (64.2) | 0.838a |
Klebsiella aero genes; n (%) | 14 | (26.4) | 16 | (30.2) | 0.830a |
Other Enterobacter spp.; n (%) | 3 | (5.7) | 3 | (5.7) | 1.000a |
aFisher’s exact test, bMann-Whitney U test. IQR: interquartile range, eGFR: estimated glomerular filtration rate, WBC: white blood cell, CRP: C-reactive protein