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. 2023 Jul 13;35:102317. doi: 10.1016/j.pmedr.2023.102317

Fig. 1.

Fig. 1

The substitution method (an example with only one group of late participants) Early participants make up the share α of the full population, late participants β, and non-participants 1-α-β. The proportion with the characteristic of interest is yα¯ among early participants and yβ¯ among late participants. The model assumes that non-participants are similar to late participants on average. The estimated population proportion ypop¯ is given by αyα¯+(1-α)yβ¯, which lies somewhere in between yα¯ and yβ¯ and corresponds to the combined area of the dark and light shaded regions.