TABLE 1.
Within-subjects’ comparison of Arc mRNA expression patterns.
| Region | Comparison | F | p | η2p | Post hoc |
| Medial prefrontal cortex | |||||
| PL | Expression type | (2,145) 14.96 |
<0.001*** | 0.51 | CYT > NUC, p = 0.003 |
| CYT > DBL, p < 0.001 | |||||
| Group *Expression type |
(6,145) 1.44 |
N.S. | – | – | |
| IL | Expression type | (2,142) 13.37 |
<0.001** | 0.42 | CYT > DBL, p < 0.001 |
| NUC > DBL, p < 0.001 | |||||
| Group *Expression type |
(6,142) 0.48 |
N.S. | – | – | |
| Amygdaloid nuclei | |||||
| mCeA | Expression type | (2,199) 5.80 |
<0.01** | 0.26 | CYT > DBL, p < 0.01 CYT > NUC, p < 0.001 |
| Group *Expression type |
(6,199) 1.26 |
N.S. | – | – | |
| lCeA | Expression type | (2,115) 2.09 |
N.S. | – | – |
| LA | Group *Expression type |
(6,115) 0.40 |
N.S. | – | – |
| Expression type | (2,121) 7.41 |
<0.01** | 0.4 | CYT > NUC, p < 0.001 | |
| BLA | Group *Expression type |
(6,121) 1.59 |
N.S. | – | – |
| Expression type | (2,199) 15.58 |
<0.001*** | 0.6 | DBL > NUC, p < 0.001 CYT > NUC, p < 0.001 |
|
| Group *Expression type |
(6,199) 0.82 |
N.S. | – | – | |
| Dorsal and ventral hippocampus | |||||
| dCA1 | Expression type | (2,310) 3.12 |
<0.05* | 0.76 | CYT > DBL, p = 0.06 |
| dCA3 | Group *Expression type |
(6,310) 1.51 |
N.S. | – | – |
| Expression type | (2,310) 8.35 |
<0.01** | 0.45 | CYT > DBL, p < 0.001 CYT > NUC, p < 0.01 |
|
| Group *Expression type |
(6,310) 4.52 |
<0.05* | 0.31 | P-same: NUC > DBL, p = 0.003 |
|
| P-same: CYT > DBL, p = 0.003 |
|||||
| M/D-different NUC > M/D-same NUC, p < 0.001 | |||||
| P-different DBL > P-same DBL, p = 0.001 | |||||
| vCA1 | Expression type | (2,22) 10.61 |
<0.001*** | 0.49 | CYT > DBL, p < 0.001 |
| Group *Expression type |
(6,220) 0.53 |
N.S. | – | – | |
| CYT > NUC, p < 0.001 | |||||
| vCA3 | Expression type | (2,202) 32.94 |
<0.001*** | 0.75 | CYT > DBL, p < 0.001 CYT > NUC, p < 0.001 |
| NUC > DBL, p < 0.001 | |||||
| Group *Expression type |
(6,202) 4.48 |
<0.05* | 0.29 | M/D-same: CYT > DBL, p = 0.002 |
|
| M/D-different: NUC > DBL, p < 0.001 |
|||||
| M/D-different: CYT > DBL, p < 0.001 |
|||||
| P-different: CYT > DBL, p = 0.002 |
|||||
| P-same: NUC > DBL, p < 0.001 |
|||||
| P-same: CYT > DBL, p = 0.003 |
|||||
Results list significant main or interaction effects of repeated measures ANOVA for each brain region, alpha (p), effect size (η2), and post hoc results indicating directionality from Bonferroni corrected t tests. *p < 0.05, **p < 0.01, ***p < 0.001.