TABLE 5.
Treatment response in different BMI groups of COPD patients after propensity score matching.
| Variables | Total (N = 372) | Low BMI (N = 96) | Normal BMI (N = 183) | High BMI (N = 93) | p-values |
|---|---|---|---|---|---|
| ΔCAT (median, IQR) | 3 (−1, 7.2) | 2 (−2, 7.0) b | 2 (−1.5, 7) b | 5 (0, 10) | 0.029 |
| MCID, n (%) | 0.040 | ||||
| Yes | 210 (58.3) | 48 (53.9) b | 98 (54.7) b | 64 (69.6) | |
| No | 150 (41.7) | 41 (46.1) b | 81 (45.3) b | 28 (30.4) | |
| CID, n (%) | 0.022 | ||||
| Yes | 80 (22.2) | 24 (27.0) b | 45 (25.1) b | 11 (12.0) | |
| No | 280 (77.8) | 65 (73.0) b | 134 (74.9) b | 81 (88.0) | |
| Exacerbations in the past year (median, IQR) | 0 (0, 1) | 0 (0, 1) | 0 (0, 1) | 0 (0, 1) | 0.907 |
| Exacerbations, n (%) | |||||
| 0 | 258 (72.1) | 61 (70.1) | 130 (72.6) | 67 (72.8) | |
| 1 | 58 (16.2) | 16 (18.4) | 30 (16.8) | 12 (13.0) | |
| ≥2 | 42 (11.7) | 10 (11.5) | 19 (10.6) | 13 (14.2) | |
| Hospitalizations in the past year (median, IQR) | 0 (0, 0) | 0 (0, 0) a , b | 0 (0, 0) | 0 (0, 0) | 0.007 |
| Hospitalizations, n (%) | 0.005 | ||||
| 0 | 307 (85.8) | 66 (75.9) a , b | 157 (87.7) | 85 (92.4) | |
| ≥1 | 51 (14.2) | 21 (24.1) a , b | 22 (12.3) | 7 (7.6) | |
| Mortality, n (%) | 14 (3.8) | 9 (9.4) a , b | 4 (2.2) | 1 (1.1) | 0.005 |
a
p < 0.05 vs. the normal-BMI group.
b
p < 0.05 vs. the high-BMI group. The bold p-values indicate statistical significance. ΔCAT, CAT scores at 6 months of visit from baseline.
BMI, body mass index; COPD, chronic obstructive pulmonary disease; CAT, COPD Assessment Test; CID, clinically important deterioration; MCID, minimal clinically important difference.