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. 2023 Jul 13;14:1166951. doi: 10.3389/fimmu.2023.1166951

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Copyright © 2023 Zhang, Pan, Xiong, Zheng, McPherson, Lee, Huang, Xu, Chen, Wang, Hildebrandt Ruiz and You

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Efficacy of aerosolized miRNA on development NTCU-induced lung SCC. (A) Experimental design. (B) Representative histological images of mouse lung squamous lesions. All images are scanned by NanoZoomer system (Hamamatsu Photonics, Hamamatsu, Japan). (C, D) Percentage of normal bronchus and SCC in treatment groups. Statistical analysis was performed using one-way ANOVA *p<0.05. (C) Efficacy of miR-Let7b on the percentage of SCC development in each lung (n = 15; *p< 0.05 and ***p< 0.001).