Table 6.

Adverse Reactions Among Case Series

Adverse Reactions		No. (%)
Patients with adverse reactions	No. of patients who reported adverse reaction	133 (40.67)
Impact on the treatment	Treatment unchanged	112 (84.21)
	Treatment modified (dose/length/etc.)	10 (7.52)
	Treatment discontinued	11 (8.27)
Patients included (with or without adverse reactions)	Total No. of patients included	327 (100)
Adverse reaction categories	Renal insufficiency/toxicity	79 (43.89)
	Electrolytes disorders	12 (6.67)
	Infusion reaction	50 (27.78)
	Rash/cutaneous reaction	1 (0.56)
	GI symptoms	18 (10.00)
	Cardiac toxicity	2 (1.11)
	Anaphylaxis	2 (1.11)
	Other	31 (17.22)
Total No. of events	Total No. of adverse reactions reported	180 (100)