Gwechenberger 1997.

Methods	Study design : randomised study
Participants	Country : Austria Setting : hospital Number of centres : 1 Numbers: VasoSeal 33, manual compression 33 Age (mean (SD)) : VasoSeal 59.8 (8.1) years, manual compression 56.9 (10.8) years Sex : VasoSeal 31 M/2 F, manual compression 24 M/5 F Inclusion criteria : patients undergoing diagnostic or therapeutic percutaneous transluminal coronary angioplasty Exclusion criteria : not stated
Interventions	Intervention 1 : VasoSeal Intervention 2 : manual compression Sheath size : not stated
Outcomes	Primary : time to haemostasis Secondary : complications (arteriovenous fistula, pseudoaneurysm, bleeding, haematoma > 6 cm in diameter)
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Quote: "randomised" Comment: insufficient information to permit judgement of high or low risk
Allocation concealment (selection bias)	Unclear risk	Insufficient information to permit judgement of high or low risk
Blinding of participants and personnel (performance bias) All outcomes	Low risk	No blinding, but review authors judged that outcomes and outcome measurements are not likely to be influenced by lack of blinding
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Insufficient information to permit judgement of high or low risk
Incomplete outcome data (attrition bias) All outcomes	Low risk	No missing data
Selective reporting (reporting bias)	Unclear risk	Study outcomes are not clearly reported
Other bias	Unclear risk	Insufficient information to permit judgement of high or low risk