Table 2.
Gene Ontology (GO) Process Term analysis for genes identified in genome-wide screen
| Gene Ontology Term | Cluster frequency | Genome frequency | Corrected p value | Genes |
|---|---|---|---|---|
| sulfate assimilation | 5 of 128 genes, 3.9% | 9 of 7166 genes, 0.1% | 0.00012 | MET3 MET5 MET8 MET10 MET14 |
| sulfur compound biosynthetic process | 10 of 128 genes, 7.8% | 82 of 7166 genes, 1.1% | 0.00102 | HOM2 HOM3 MET2 MET3 MET5 MET6 MET10 MET14 PDA1 SAM1 |
| sulfur amino acid metabolic process | 8 of 128 genes, 6.2% | 49 of 7166 genes, 0.7% | 0.00124 | HOM2 HOM3 MET2 MET3 MET5 MET6 MET14 SAM1 |
| hydrogen sulfide metabolic process | 4 of 128 genes, 3.1% | 8 of 7166 genes, 0.1% | 0.00395 | MET3 MET5 MET10 MET14 |
| hydrogen sulfide biosynthetic process | 4 of 128 genes, 3.1% | 8 of 7166 genes, 0.1% | 0.00395 | MET3 MET5 MET10 MET14 |
128 genes with ΔOD595 values greater than or equal to 0.079 in screen for genes with potential roles in ER protein degradation were analyzed using the Gene Ontology Term Finder at the Saccharomyces Genome Database (https://www.yeastgenome.org/goTermFinder) using a p-value cutoff of 0.01. No Function or Component GO Terms were significantly enriched for the input list of 128 genes.