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. 2023 Feb 21;13(7):3080–3092. doi: 10.1016/j.apsb.2023.02.008

Table 1.

In vitro antifungal activity of photocaged FLC derivatives under light or non-light conditions (MIC80a, μg/mL).

Compd. Structure (R) C. albicans SC5314
C. neoformans
H99
black hvb black hvb
A1 MNPPOC >64 0.5 64 2
A2 DMNB >64 1 64 4
A3 DMNBOC 16 16 64 64
A4 MNPEOC 64 2 32 8
FLC / 0.25 0.25 1 1

2.1.

a

The minimum concentration of the compound at which the inhibition rate is greater than or equal to 80%.

b

Light condition: 365 nm, 25 mW/cm2, 3 min.