Table 1.
In vitro antifungal activity of photocaged FLC derivatives under light or non-light conditions (MIC80a, μg/mL).
| Compd. | Structure (R) |
C. albicans SC5314 |
C. neoformans H99 |
||
|---|---|---|---|---|---|
| black | hvb | black | hvb | ||
| A1 | MNPPOC | >64 | 0.5 | 64 | 2 |
| A2 | DMNB | >64 | 1 | 64 | 4 |
| A3 | DMNBOC | 16 | 16 | 64 | 64 |
| A4 | MNPEOC | 64 | 2 | 32 | 8 |
| FLC | / | 0.25 | 0.25 | 1 | 1 |

The minimum concentration of the compound at which the inhibition rate is greater than or equal to 80%.
Light condition: 365 nm, 25 mW/cm2, 3 min.