Table 2.

Demographics of IBD-BIOM Validation Set

	CD (n = 123)	SC (n = 84)	P value SC vs CD	Healthy volunteers (n = 114)	P value HL vs CD
Age, median (IQR)	32.4 (24.9–50.7)	32.8 (26.4–45.5)	.9a	32.3 26.4–40.6)	.4a
Females, n (%)	58 (47.9)	39 (52.7)	.6b	59 (50.4)	.8b
Smoking status
Current	53	17	Current vs ex/never	24	Current vs ex/never
Ex	29	17	.005	32	.0005
Never	39	40	Ever vs never	56	Ever vs never
Unknown	0	0	.004	5	.008
CRP	8 (2–23)	0 (0–3.5)	.006a
ESR	18 (5–39)	6 (4.5–7.5)	.002a
FC	495 (135–828)	19 (19–37)	.0001a

CD, Crohn’s disease; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; FC, fecal calprotectin; HL, healthy laboratory volunteers; IQR, interquartile range; SC, symptomatic control subjects; UC, ulcerative colitis.

Adapted with permission from Ventham et al.

^aWilcoxon rank sum test.

^bChi-square test.