TABLE 2.
Baseline Demographic and Clinical Characteristics of the Study Population (2006-2014)
| Full sample N = 27,394 n (%) | Group 0 | Group 1 | Group 2 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Cases N = 8,167 n (%) | Controls N = 6,887 n (%) | P value | Cases N = 3,693 n (%) | Controls N = 4,517 n (%) | P value | Cases N = 2,258 n (%) | Controls N = 1,872 n (%) | P value | ||
| Follow-up time, mean (SD), m | 47 (27.0) | 44 (24.5) | 51 (28.5) | < 0.001a | 44 (25.7) | 52 (28.7) | < 0.001a | 43 (24.7) | 51 (29.3) | < 0.001a |
| Age, mean (SD), y | 73 (12.2) | 76 (9.2) | 71 (15.2) | < 0.001a | 72 (9.4) | 68 (9.1) | < 0.001a | 82 (7.3) | 72 (16.7) | < 0.001a |
| Age category, y | ||||||||||
| < 65 | 4,299 (16) | 807 (10) | 1,784 (26) | < 0.001 | 412 (11) | 655 (15) | < 0.001 | 78 (3) | 563 (30) | < 0.001 |
| 65-74 | 9,269 (34) | 1,616 (20) | 1,392 (20) | 2,622 (71) | 3,639 (81) | 0 (0) | 0 (0) | |||
| 75-84 | 9,929 (36) | 4,700 (58) | 2,833 (41) | 0 (0) | 0 (0) | 1,443 (64) | 953 (51) | |||
| > 84 | 3,897 (14) | 1,044 (13) | 878 (13) | 659 (18) | 223 (5) | 737 (33) | 356 (19) | |||
| Sex | ||||||||||
| Male | 10,540 (38) | 2,965 (36) | 2,350 (34) | 0.005 | 2,723 (74) | 2,275 (50) | < 0.001 | 162 (7) | 65 (3) | < 0.001 |
| Female | 16,854 (62) | 5,202 (64) | 4,537 (66) | 970 (26) | 2,242 (50) | 2,096 (93) | 1,807 (97) | |||
| Race | ||||||||||
| White | 25,363 (93) | 7,830 (96) | 6,470 (94) | < 0.001 | 3,481 (94) | 4,066 (90) | < 0.001 | 1,865 (83) | 1,651 (88) | < 0.001 |
| African American | 1,401 (5) | 152 (2) | 240 (3) | 212 (6) | 451 (10) | 197 (9) | 149 (8) | |||
| Other | 630 (2) | 185 (2) | 177 (3) | 0 (0) | 0 (0) | 196 (9) | 72 (4) | |||
| Count of HCC conditionsb | ||||||||||
| 0 | 4,751 (17) | 916 (11) | 1,257 (18) | < 0.001 | 599 (16) | 1,599 (35) | < 0.001 | 94 (4) | 286 (15) | < 0.001 |
| 1 | 5,343 (20) | 1,384 (17) | 1,569 (23) | 838 (23) | 1,187 (26) | 53 (2) | 312 (17) | |||
| 2-3 | 8,399 (31) | 2,372 (29) | 2,447 (36) | 839 (23) | 815 (18) | 1,118 (50) | 808 (43) | |||
| > 3 | 8,901 (32) | 3,495 (43) | 1,614 (23) | 1,417 (38) | 916 (20) | 993 (44) | 466 (25) | |||
| Region | ||||||||||
| Midwest | 7,235 (26) | 2,149 (26) | 1,794 (26) | 0.296 | 1,043 (28) | 1,226 (27) | 0.171 | 529 (23) | 494 (26) | 0.131 |
| Northeast | 5,391 (20) | 1,626 (20) | 1,428 (21) | 672 (18) | 763 (17) | 500 (22) | 402 (21) | |||
| South | 10,612 (39) | 3,192 (39) | 2,610 (38) | 1,406 (38) | 1,795 (40) | 906 (40) | 703 (38) | |||
| West and other/unknownc | 4,156 (15) | 1,200 (15) | 1,055 (15) | 572 (15) | 733 (16) | 323 (14) | 273 (15) | |||
| LIS | ||||||||||
| Yes | 9,892 (36) | 3,095 (38) | 2,713 (39) | 0.159 | 1,152 (31) | 1,138 (25) | < 0.001 | 970 (43) | 824 (44) | 0.642 |
| No | 14,877 (54) | 4,256 (52) | 3,490 (51) | 2,275 (62) | 3,003 (66) | 1,028 (46) | 825 (44) | |||
| Missing | 2,625 (10) | 816 (10) | 684 (10) | 266 (7) | 376 (8) | 260 (12) | 223 (12) | |||
The table presents column percentages for categorical variables.
a Based on two-sample t-test.
b HCC is defined based on the health care utilization in the 12 months before index date.
c The West and other/unknown regions were combined to avoid cell sizes less than 11 per data use agreement.
HCC = hierarchical condition categories; LIS = low-income subsidy; m = month; y = year.