TABLE 2.
Total 1-Year Utilization and Costs Prior to Diagnosis for Beneficiaries With AV and Matched Controls (AB Sample)
| Descriptive statistics | Adjusted regression modela | ||||||
|---|---|---|---|---|---|---|---|
| Beneficiaries without AV (N = 730) | Beneficiaries with AV (N = 730) | IRRs | Beneficiaries without AV (N = 730) | Beneficiaries with AV (N = 730) | |||
| Mean (SD) | Median (IQR) | Mean (SD) | Median (IQR) | IRR (95% CI) | Predicted means (95% CI) | Predicted means (95% CI) | |
| Medical service payments, USDb | |||||||
| Total Medicare Parts A and B payments | 8,568 (23,802) | 1-977 (601-7,392) | 18,772 (28,049) | 8,254 (2,497-24,799) | 2.94c (2.44-3.53) | 7,346 (6,165-8,528) | 21,582 (18,908-24,255) |
| Total beneficiary Parts A and B payments | 1,513 (2,585) | 619 (263-1,818) | 3,414 (4,063) | 2,128 (783-4,233) | 2.47c (2.14-2.84) | 1,444 (1,277-1,611) | 3,563 (3,248-3,878) |
| Drug payments, USDb | |||||||
| Total Medicare Part B drug payments | 260 (1,652) | 16 (0-68) | 627 (3,147) | 38 (0-207) | 2.31c (1.65-3.23) | 231 (156-306) | 534 (356-711) |
| Total beneficiary Part B drug payments | 58 (421) | 0 (0-3) | 152 (809) | 0 (0-16) | 3.79c (2.20-6.52) | 61 (21-101) | 232 (46-418) |
| Health care utilization | |||||||
| Acute inpatient stays | 0.22 (0.63) | 0 (0-0) | 0.61 (1.08) | 0 (0-1) | 2.77c (2.19-3.51) | 0.22 (0.18-0.27) | 0.61 (0.53-0.69) |
| Hospital outpatient visits | 6.87 (18.86) | 2 (0-6) | 22.78 (53.00) | 5 (1-15) | 2.69c (2.22-3.27) | 7.46 (6.35-8.57) | 20.08 (16.71-23.45) |
| Emergency department visits | 0.73 (1.96) | 0 (0-1) | 1.06 (1.97) | 0 (0-1) | 1.57c (1.28-1.94) | 0.70 (0.58-0.82) | 1.10 (0.95-1.26) |
| Part B drug events | 2.88 (6.28) | 2 (0-3) | 4.73 (12.89) | 2 (0-4) | 1.47c (1.23-1.76) | 2.97 (2.55-3.38) | 4.36 (3.67-5.06) |
| Part B physician office services | 7.67 (7.75) | 6 (2-10) | 12.09 (10.71) | 10 (5-16) | 1.62c (1.47-1.79) | 7.57 (7.02-8.13) | 12.27 (11.08-13.47) |
| Imaging | 4.36 (6.28) | 2 (0-6) | 9.70 (9.90) | 7 (3-14) | 2.40c (2.11-2.71) | 4.22 (3.80-4.64) | 10.11 (9.31-10.90) |
| Tests | 14.13 (25.09) | 7.5 (1-18) | 27.49 (32.24) | 16.5 (5-38) | 2.08c (1.80-2.39) | 13.72 (12.19-15.24) | 28.47 (25.14-31.80) |
| Other procedures | 7.77 (21.51) | 2 (0-7) | 10.58 (19.68) | 5 (1-12) | 1.72c (1.41-2.11) | 6.87 (5.74-8.00) | 11.83 (10.19-13.47) |
| Durable medical equipment | 2.36 (6.75) | 0 (0-1) | 3.33 (7.52) | 0 (0-2) | 1.54d (1.16-2.03) | 2.28 (1.80-2.76) | 3.50 (2.85-4.15) |
| Other Part B carrier events | 5.00 (21.13) | 1 (0-4) | 7.88 (27.05) | 3 (0-9) | 1.82c (1.50-2.21) | 4.48 (3.71-5.25) | 8.15 (6.91-9.39) |
a Adjusted for age, sex, race, dual Medicaid enrollment or Part D low-income subsidy, entitlement due to disability, and US region.
b Health care costs were measured in the 1-year period prior to the index date in 2016, resulting in a combination of 2015 and 2016 USD.
c P < 0.001.
d P = 0.003.
AB = beneficiaries with Part A/B coverage; AV = antineutrophil cytoplasmic antibody vasculitis; IQR = interquartile range; IRR = incidence rate ratio; USD = US dollars.