TABLE 2.
Model Results for Eculizumab and Efgartigimod Compared with Conventional Therapy
| Deterministic analysis | Total costs $ | QALYs | LYs | Incremental results | |
|---|---|---|---|---|---|
| Cost/QALY gained (same as cost per evLYG) | Cost/LY gaineda | ||||
| Comparison of eculizumab to conventional therapy | |||||
| Eculizumab plus CT | 855,400 | 1.13 | 1.93 | 5,210,000 | N/A |
| CT alone | 95,500 | 0.98 | 1.93 | – | – |
| Comparison of efgartigimod to conventional therapy | |||||
| Efgartigimod plus CTb | 692,700 | 1.27 | 1.93 | 2,076,000 | N/A |
| CT alone | 94,800 | 0.98 | 1.93 | – | – |
a There were no differences in survival. Cost per life-year gained could not be calculated, whereas cost per evLYG is equal to the cost per QALY gained.
b Efgartigimod was evaluated using a placeholder price.
evLYG = equal value of life-years gained; CT = conventional therapy; LY = life-year; N/A = not applicable; QALY = quality-adjusted life-year.