TABLE 2.
Claims-Based MCS and EHR-Based MRCI Scores Across Patient Subgroupings at 2 Study Sites
| Patient group | MRCI Mean (SD) | MCS Mean (SD) | Health Partners | Johns Hopkins Health System | ||||
|---|---|---|---|---|---|---|---|---|
| Spearman rhoa | % Exact | MRCI Mean (SD) | MCS Mean (SD) | Spearman rhoa | % Exact | |||
| Full sample | 11.8 (11.6) | 43.3 (52.5) | 0.556 | 79.0 | 24.3 (33.5) | 59.3 (73.3) | 0.627 | 76.5 |
| Age, y | ||||||||
| < 20 | 10.8 (12.2) | 27.8 (31.3) | 0.526 | 50.7 | 17.0 (19.4) | 37.7 (46.7) | 0.609 | 61.0 |
| 20-34 | 11.6 (12.9) | 32.7 (40.3) | 0.529 | 87.2 | 20.1 (26.6) | 45.6 (51.6) | 0.552 | 86.3 |
| 35-44 | 13.1 (15.9) | 39.2 (47.2) | 0.550 | 85.8 | 25.2 (31.9) | 60.8 (67.3) | 0.611 | 85.1 |
| 45-54 | 14.6 (16.4) | 48.6 (57.9) | 0.574 | 83.7 | 33.3 (44.9) | 87.4 (95.4) | 0.654 | 81.1 |
| 55-64 | 12.8 (14.5) | 58.6 (63.2) | 0.589 | 83.1 | 38.2 (48.1) | 102.9 (102.6) | 0.642 | 78.9 |
| Sex | ||||||||
| Female | 12.2 (14.1) | 45.7 (54.6) | 0.565 | 80.1 | 24.8 (34.5) | 61.8 (75.6) | 0.624 | 78.3 |
| Male | 9.3 (8.8) | 39.5 (48.7) | 0.545 | 77.4 | 23.4 (31.4) | 54.6 (68.5) | 0.635 | 73.0 |
| Count of chronic conditions treated during year | ||||||||
| 1 | 10.8 (10.5) | 25.6 (23.8) | 0.449 | 79.6 | 15.3 (15.0) | 34.7 (35.1) | 0.544 | 75.3 |
| 2 | 17.1 (18.0) | 33.5 (32.3) | 0.466 | 80.9 | 18.2 (18.3) | 43.3 (43.7) | 0.509 | 78.9 |
| 3+ | 4.9 (5.1) | 66.9 (67.2) | 0.529 | 79.5 | 37.9 (44.8) | 95.1 (93.2) | 0.561 | 76.8 |
| Count of active ingredients in filled prescriptions | ||||||||
| 1 | 6.3 (5.8) | 7.9 (6.7) | 0.336 | 80.4 | 8.5 (9.3) | 13.1 (14.8) | 0.412 | 71.9 |
| 2 | 14.6 (15.5) | 13.6 (10.5) | 0.226 | 80.7 | 11.5 (11.3) | 21.7 (19.6) | 0.445 | 72.7 |
| 3+ | 11.8 (11.6) | 52.7 (56.1) | 0.475 | 78.5 | 29.9 (37.4) | 75.8 (79.6) | 0.557 | 77.3 |
a Indicates test significance at P < 0.001.
EHR = electronic health record; MCS = medication complexity score (novel measure developed by this study, calculated from pharmacy claims data); MRCI = Medication Regimen Complexity Index (established measure calculated from electronic health records); y = years.