| RIFLE |
Dialysis for > 3 months |
| Renal replacement therapy for > 4 weeks |
| Serum creatinine increase relative to baseline (1.5x for risk, 2x for injury, 3x or creatinine ≥ 354 µmol/L with acute rise of ≥ 44 µmol/L for failure) |
| Glomerular filtration rate decrease relative to baseline (> 25% for risk, > 50% for injury, > 75% for failure) |
| Urine output (< 0.5 mL/kg/h through 6 hours for risk, < 0.5 mL/kg/h through 12 hours for injury, < 0.3 mL/kg/h through 24 hours or anuria for 12 hours for failure) |
| AKIN |
Absolute increase in serum creatinine concentration > 26.4 µmol/L |
| Increase in serum creatinine concentration > 1.5x relative to baseline |
| Urine output < 0.5 mL/kg/h for > 6 hours |
| KDIGO |
Serum creatinine |
| Urine output |
| RIFLE – Risk, Injury, Failure, Loss of kidney function, and End-stage kidney disease, criteria first described by Bellomo et al. (5). AKIN – Acute Kidney Injury Network, criteria first described by Mehta et al. (4). KDIGO – Kidney Disease Improving Global Outcomes, criteria first described by the Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group (6). |