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. 2023 Aug 5;33(3):030502. doi: 10.11613/BM.2023.030502

Table 3. Most commonly used criteria for diagnosing acute kidney injury.

Criteria name Components
RIFLE Dialysis for > 3 months
Renal replacement therapy for > 4 weeks
Serum creatinine increase relative to baseline (1.5x for risk, 2x for injury, 3x or creatinine ≥ 354 µmol/L with acute rise of ≥ 44 µmol/L for failure)
Glomerular filtration rate decrease relative to baseline (> 25% for risk, > 50% for injury, > 75% for failure)
Urine output (< 0.5 mL/kg/h through 6 hours for risk, < 0.5 mL/kg/h through 12 hours for injury, < 0.3 mL/kg/h through 24 hours or anuria for 12 hours for failure)
AKIN Absolute increase in serum creatinine concentration > 26.4 µmol/L
Increase in serum creatinine concentration > 1.5x relative to baseline
Urine output < 0.5 mL/kg/h for > 6 hours
KDIGO Serum creatinine
Urine output
RIFLE – Risk, Injury, Failure, Loss of kidney function, and End-stage kidney disease, criteria first described by Bellomo et al. (5). AKIN – Acute Kidney Injury Network, criteria first described by Mehta et al. (4). KDIGO – Kidney Disease Improving Global Outcomes, criteria first described by the Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group (6).