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. Author manuscript; available in PMC: 2023 Jul 27.
Published in final edited form as: Neuropharmacology. 2020 Feb 12;168:108007. doi: 10.1016/j.neuropharm.2020.108007

Fig. 3.

Fig. 3.

lOFC (n = 16), but not mOFC (n = 14) inactivation significantly decreased cue-induced reinstatement of EtOH seeking. (A) Extinction curve for mOFC-implanted rats. (B) Extinction curve for lOFC-implanted rats. (C) mOFC inactivation did not significantly alter active nosepokes or ethanol-cues received. Inactive nosepokes were slightly, but significantly decreased after mOFC inactivation (t(13) = 2.69, p = 0.02, paired t-test). (D) lOFC inactivation significantly decreased active nosepokes (t(15) = 3.31, p = 0.0048, paired t-test), and “infusions” received, i.e., cues elicited (t(15) = 3.25, p = 0.0054)., but not inactive nosepokes. See main text for additional analyses. *p < 0.05, **p < 0.01, ***p < 0.005.