Table 2.
Characteristics of included studies.
| No. | Study | Type of Study Clinical trial/retrospective | Group Sample Size (# of crowns) | Participants | Intervention | Control | Method of impression | Method of fabrication Pressed/milled | Follow-up Time |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Ahn et al., 2020 (Ahn et al., 2022) | Clinical trial |
CEREC, TRIOS N = 12 EZIS: N:16 |
Health status: without any general disease Age: 24 to 83 y Gender: 10 male and 30 female |
MLD based on CAD/CAM system: CEREC EZIS TRIOS |
– | Digital impression CEREC group: CEREC Bluecam EZIS group: EZIS PO TRIOS group: TRIOS 3 |
CAD/CAM Milled |
Base line, 1 month, 2 mmonts, 3 months & 6 months |
| 2 | Hammoudi et al., 2020 (Hammoudi et al., 2022) | Clinical trial |
LDC N = 362 TZ N = 351 |
Health status: Good overall dental health Age: 25 to 63 years Gender: 45 males and 17 females |
LDC | TZ | Conventional (Polyether material) | Not mentioned | Base line, 14 months, 31 months, 39 months, 54 months & 65 months |
| 3 | Forrer et al., 2020 (Forrer et al., 2020) | Retrospective study |
CC: N = 20 CP: N = 39 CV: N = 16 |
Health status: Not mentioned Age: Not mentioned Gender: 30 males and 52 females |
CC CP CV |
– | Not mentioned | CAD/CAM Milled | Base line & 4.08 ± 0.36 years |
| 4 | Scutella et al., 2020 (Scutella et al., 2020) | Retrospective study | N = 122 | Health status: Not mentioned Age: Mean age 56.4 years Gender: 29 male and 58 female, |
LDC | – | Digital impressions (CEREC 3D Blue-cam) | Chairside CAD/CAM Milled | 5 years |
| 5 | Seidel et al., 2020 (Seidel et al., 2020) | Clinical trial | N = 15 | Health status: Good Age: 18 years and above Gender: Not mentioned |
MLD | ZVGC | Conventional (polyvinylsiloxane material) | CAD/CAM Milled | Base line, 1 year, 2 years & 3 years |
| 6 | Aziz et al., 2019 (Aziz et al., 2019) | Retrospective clinical study | N = 40 | Health Status: Not mentioned Age: 29–79 years Gender: 12 males and 20 females |
LDGC CAD-CAM | CL | Digital impression (CEREC Omnicam) | CAD/CAM Milled | 4 years |
| 7 | Samer et al., 2017 (Samer et al., 2017) | Cross sectional study/retrospective | N = 88 | Health status: Medically fit Age: 18–64 years Gender: 16 males and 31 females |
LDC | – | Not mentioned | Pressed | Not clearly mentioned |
| 8 | Schimtz et al., 2017 (Schmitz et al., 2017) | Retrospective clinical study | N: 627 | Health status: Not mentioned Age: Not mentioned Gender: Not mentioned |
MLD | – | Not mentioned | Not mentioned | 48.17 ± 27.72 months |
| 9 | Rauch et al., 2017 (Rauch et al., 2017) | Clinical trial | N = 41 | Health status: Healthy Age: 26.2–73.8 years Gender: 13 males and 21 females |
LDC | – | Digital impressions (Cerec 3 units) | CAD/CAM milled | Base line, 6 months, 1 year, 2 years, 3 years, 4 years, 5 years, & 6 years |
| 10 | Teichmann et al., 2017 (Teichmann et al., 2017) | Prospective clinical study |
LDFDP: N = 33 LDC: N = 106 LDIMP: N = 32 Other-LD: N = 13 |
Health status: Not mentioned Age: LDC: mean age 23.9 LDFDP: mean age 40.7 LDIM: mean age 40.7 Gender: 30 males and 38 females |
LDC | -LDFDP -LDIMP - Other-LD |
Conventional (Polyether or A-Silicon material) | Pressed | Base line, 6 months, 1 year, 2 years, 3 years, 5 years & 7 years |
| 11 | Seydler et al., 2015 (Seydler & Schmitter, 2015) | Clinical trial | N = 30 | Health status: Not mentioned Age: Less than 18 years Gender: 22 males and 38 Females |
LDC | VZ | Digital Impression (Blue cam; Sirona Dental Systems) | CAD/CAM Milled | 1 year & 2 years |
| 12 | Toman et al., 2015 (Toman & Toksavul, 2015) | Clinical trial | N = 125 | Health status: Not mentioned Age: Not mentioned Gender: 13 males and 21 females |
LDC | – | Conventional (Venylpolyvinyl siloxane material) | Pressed | Base line, 6 months, then annually |
| 13 | Batson et al., 2014 (Batson et al., 2014) | Clinical trial |
MC: N = 12 LDC, ZC N = 10 |
Health status: Not mentioned Age: Not mentioned Gender: Not mentioned |
LDC | MC ZC CL tooth |
Digital Impression: iTero |
CAD/ CAM Milled |
Base line, 1 month & 6 months |
| 14 | Esquivel-Upshaw et al., 2013 (Esquivel-Upshaw et al., 2013) | Clinical trial | N = 12 | Health status: Good overall dental health Age: Above 18 Gender: Not mentioned |
LDC LDCV |
MC | Conventional (Polyvinyl siloxane) | Not mentioned | Base line, 1 year, 2 years & 3 years |
| 15 | Cortellini et al., 2012 (Cortellini & Canale, 2012) | Clinical trial | N = 235 | Health status: Healthy Age: 20–61 years Gender: 32 males and 44 females |
LDC | – | Conventional (Polyether material) | -CAD/CAM Milled -Pressed |
Base line, 1 year, 2 years & 3 years |
| 16 | Gehrt et al., 2012 (Gehrt et al., 2013) | Clinical trial | Adhesively luted:N = 72 Glass-ionomer cement: N = 32 |
Health status: Not mentioned Age: Mean age, 34 ± 9.6 years Gender: 15 males and 26 females |
LDC | – | Conventional (Polyether material) | Pressed | Base line, 5 years, 6 years, 7 years, 8 years & 9 years |
| 17 | Fasbinder et al., 2010 (Fasbinder et al., 2010) | Clinical trial |
LDC-4: N = 23 LDC-5: N = 39 |
Health status: Not mentioned Age: Not mentioned Gender: Not mentioned |
LDC: -LDC-4 -LDC-5 |
– | Digital impression | CAD/CAM Milled | Base line, 6 months, 1 year & 2 years |
| 18 |
Suputtamongkol et al., 2008 (Suputtamongkol et al., 2008) |
Clinical trial | N = 10 | Health status: Good to excellent overall dental health. Age: 20–56 years Gender: 5 males & 25 females |
LLD: -LDC-1 -LDC-2 -LDC-3 |
– | Conventional (Polyvinyl siloxane Material) | Pressed | Base line, 1 year & 2 years |
| 19 | Taskonak et al., 2006 (Taskonak & Sertgöz, 2006) | Clinical trial | N = 20 | Health status: Not mentioned Age: 21–59 years Gender: 3 males and 12 females |
LDC | LDFPD |
Conventional (Polyvinyl siloxane material) | Pressed | Base line, 1 year & 2 years |
MLD: Monolithic Lithium Disilicate crown, VZ: zirconia frameworks veneered with CAD/CAM-produced lithium disilicate ceramic, D: Day, M: Month, Y: Year, B: Baseline, NA: Not applicable, LLD: Layered lithium disilicate crowns, LDC-1: Lithium Disilicate crown cemented with Variolink II resin cement (Ivoclar Vivadent), LDC-2: Lithium Disilicate crown cemented with temporary cement. retrieved after 1 year of insertion., LDC-3: Lithium Disilicate crown cemented with temporary cement. retrieved after 2 years of insertion, LDC-4: Lithium Disilicate crown cemented with a self-etching, dual-curing cement with a self-etching primer and adhesive, LDC-5: Lithium Disilicate crown cemented with an experimental self-adhesive, dual-curing cement, ZVGC: zirconia coping hand- veneered with glass–ceramic, LD: Lithium disilicate, LDGC CAD-CAM: Lithium disilicate glass–ceramic (LDGC) computer-aided design (CAD)-computer- aided manufacturing (CAM), CL: Contralateral, CP: Pressed Lithium Disilicate Crowns, CV: veneered pressed lithium disilicate crowns, CC: computer-aided design and computer-aided manufacturing lithium disilicate crowns, FPDC: Veneered zirconia based FPD, FPDM: Metal Ceramic FPD, MC: Metal Crowns, LDC: Lithium Disilicate Crowns, ZC: Zirconia Crowns, LDFDP: Lithium disilicate fixed dental prosthesis, LDIMP: Lithium disilicate implant-supported crowns, Other-LD: resin-bonded FDPs, inlay-retained FDP, implant FDP, ILD: In direct lithium disilicate restorations (inlay, partial crown and crown), LDCV: Lithium disilicate core ceramic/veneer ceramic crowns, ZFPD: Zirconia Fixed Partial Denture, ILDC: implant supported lithium disilicate crowns, TZ: Translucent zirconia crown.