TABLE 2.
Serum IgG antibody to S. mutans A32-2 fimbriae, S. mutans A32-2 whole cells, and CTB
| Group | Immunization treatment | ELISA
absorbance valuesa
|
||
|---|---|---|---|---|
| S. mutans fimbriae | CTB | WC | ||
| A | Vaccine and adjuvant | 0.722 ± 0.047 | 0.644 ± 0.038 | 1.183 ± 0.108 |
| B | None | 0.370 ± 0.032 | 0.060 ± 0.014 | 0.717 ± 0.062 |
| C | Adjuvant alone | 0.379 ± 0.034 | 0.480 ± 0.041 | 0.760 ± 0.072 |
a
Mean ± SEM (n = 28). P values are as follows: for S. mutans fimbriae, A versus B = 0.0001, A versus C = 0.0001, and B versus C = 0.9793; for CTB, A versus B = 0.0001, A versus C = 0.0451, and B versus C = 0.0001; and for whole cells (WC), A versus B = 0.0001, A versus C = 0.0001, and B versus C = 0.9023. Results with S. mutans fimbriae and WC for groups B and C were not significantly different (P > 0.05) as determined by Tukey’s procedure.