Table 3. Mean Growth Inhibition Percent on 60 NCI Tumor Cell Lines and Percent Growth Inhibition on MCF-7 at 10 μM.
| code | mean growth inhibition (%)* | growth inhibition on MCF-7 (%) | code | mean growth inhibition (%)* | growth inhibition on MCF-7 (%) |
|---|---|---|---|---|---|
| 1A | 35.16 | 79.52 | 4B | 16.26 | 65.72 |
| 1B | 5.92 | 60.72 | 4C | 34.08 | 65.17 |
| 1C | 29.47 | 75.83 | 4D | 21.6 | 65.90 |
| 1D | 5.44 | 46.05 | 4E | no inhibition | 19.53 |
| 1E | 26.61 | 73.36 | 4F | 1.51 | 19.33 |
| 1F | 10.99 | 24.75 | 5 | 7 | no inhibition |
| 2A | 8.37 | 3.34 | 5A | 51.94 | 89 |
| 2B | 44.30 | 90.87 | 5B | 4.88 | 1.65 |
| 2C | 48.05 | 86.30 | 5C | 17.08 | 30.88 |
| 2D | 33.90 | 81.53 | 5D | 26.67 | 68.95 |
| 2E | 43.26 | 84.70 | 5E | 10.9 | 36.69 |
| 2F | 6.90 | 2.30 | 5F | 0.12 | 0.50 |
| 3B | 5.02 | 38.78 | 5G | 17.01 | 31.83 |
| 3D | 43.96 | 76.86 | 6B | 31.53 | 83.81 |
| 3E | 22.84 | 63.13 | 6D | 24.07 | 64.30 |
| 3F | 5.16 | 13.79 | 6E | 5.84 | 18.29 |
| 3G | 22.74 | 23.67 | 6F | 5.43 | 14.08 |
| 4 | ≥100 | ≥100 | 6G | 22.39 | 37.33 |
| 4A | no inhibition | 6.63 | TAM | ≥100 | ≥100 |
*
Data obtained from NCI in vitro disease-oriented human tumor cell screen. Compounds tested at a concentration of 10 μM in triplicates.