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. 2023 Jul 11;8(29):25903–25923. doi: 10.1021/acsomega.3c01682

Table 9. Pharmacokinetics of Compound 2F in Male and Female C57BL/6 Mice.

          Cmax (ng/mL)
 AUClast (h ng/mL)
 AUCinf
route dose mg/kg sex t1/2 (hr) Tmax (hr) Mean SE Mean SE (h ng/mL)
PO 400 M 8.5 4 9400 2680 10,300 2030 119,000
PO 400 F 8.2 0.5 3540 794 47,800 6850 55,400