Table 3. Predicted Biological Activity of All Compounds (1–6) Using PASS Softwarea,b,c.
| cancer
disorder treatment |
antineoplastic
(breast cancer) |
|||
|---|---|---|---|---|
| ligand | Pa | Pi | Pa | Pi |
| 1 | 0.266 | 0.149 | 0.512 | 0.018 |
| 2 | 0.266 | 0.149 | 0.512 | 0.018 |
| 3 | 0.266 | 0.149 | 0.512 | 0.018 |
| 4 | – | – | – | – |
| 5 | – | – | – | – |
| 6 | – | – | – | – |
| A23 | 0.337 | 0.052 | 0.720 | 0.005 |
| AG9 | 0.259 | 0.158 | 0.716 | 0.005 |
Pa: probability “to be active”.
Pi: probability “to be inactive”.
AG9: Tyrphostin 1; A23: Tyrphostin 23.