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. 2023 Jul 12;8(29):25817–25831. doi: 10.1021/acsomega.3c01123

Table 3. Predicted Biological Activity of All Compounds (16) Using PASS Softwarea,b,c.

  cancer disorder treatment
antineoplastic (breast cancer)
ligand Pa Pi Pa Pi
1 0.266 0.149 0.512 0.018
2 0.266 0.149 0.512 0.018
3 0.266 0.149 0.512 0.018
4
5
6
A23 0.337 0.052 0.720 0.005
AG9 0.259 0.158 0.716 0.005
a

Pa: probability “to be active”.

b

Pi: probability “to be inactive”.

c

AG9: Tyrphostin 1; A23: Tyrphostin 23.