Table 4.
Multivariate analysis for prediction of outcomes
| Characteristic | MACE | MACCE | ||||
|---|---|---|---|---|---|---|
| Multivariate HR (95% CI) | Wald x² | P value | Multivariate HR (95% CI) | Wald x² | P value | |
| Age (year) | 1.00 (0.98–1.02) | 0.005 | 0.94 | 1.00 (0.99–1.02) | 0.288 | 0.59 |
| Male | 0.98 (0.67–1.45) | 0.007 | 0.93 | 1.10 (0.78–1.56) | 0.293 | 0.59 |
| Hyperlipidemia | 1.93 (1.34–2.77) | 12.413 | < 0.001 | 1.61 (1.18–2.21) | 8.800 | 0.003 |
| Current smoking | 1.19 (0.80–1.77) | 0.739 | 0.39 | 1.06 (0.74–1.52) | 0.111 | 0.74 |
| High-risk plaque | 2.67 (1.68–4.24) | 17.083 | < 0.001 | 2.35 (1.52–3.64) | 14.686 | < 0.001 |
| Leiden score | 1.43 (0.98–2.08) | 3.508 | 0.06 | 1.50 (1.07–2.08) | 5.676 | 0.02 |
| CT-FFR ≤ 0.75 | 1.40 (0.90–2.16) | 2.229 | 0.14 | 1.43 (0.96–2.13) | 3.012 | 0.08 |
| GΔCT-FFR ≥ 0.20 | 2.88 (1.76–4.70) | 17.734 | < 0.001 | 2.37 (1.53–3.66) | 15.041 | < 0.001 |
CI confidence interval, CT-FFR coronary computed tomography angiography-derived fractional flow reserve, GΔCT-FFR global ΔCT-FFR (sum of the trans-lesional CT-FFR gradient in all epicardial vessels), HR hazard ratio, MACE major adverse cardiovascular events, MACCE major adverse cardiovascular and cerebrovascular events