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. 2023 Jul 27;25:43. doi: 10.1186/s12968-023-00946-9

Table 4.

Residual functional, haemodynamic, and cardiac parameters at 6 month follow up assessment

Groups P-values
Control
(n = 20)
Repair
(n = 30)
Replace
(n = 22)
All groups Control vs repair Control vs replace Repair vs replace
Systolic BP (mmHg) 125 ± 14 126 ± 12 125 ± 15 0.975
Diastolic BP (mmHg) 73 ± 10 80 ± 11 77 ± 11 0.134
Heart rate (bpm) 68 ± 11 75 ± 15 71 ± 8.3 0.141
6MWT distance (m) 393 ± 109 422 ± 82 422 ± 111 0.586
NYHA (mean) 1.45 ± 0.7 1.1 ± 0.3 1.1 ± 0.3 0.087
LVEDVi (ml/m2) 117 ± 28 94 ± 28 94 ± 25 0.005 0.011 0.016 1
LVESVi (ml/m2) 48 ± 15 52 ± 23 52 ± 20 0.863
LVSVi (ml/m2) 69 ± 15 42 ± 9.3 42 ± 8.6 < 0.001 < 0.001 < 0.001 1
LVEF (%) 59 ± 5 47 ± 9.2 46 ± 8.1 < 0.001 < 0.001 < 0.001 1
Effective forward-LVEF(%) 36 ± 8.9 37 ± 8.7 41 ± 8.9 0.241
LVMi (g/m2) 54 ± 11 59 ± 15 60 ± 17 0.307
LA volume indexed (ml/m2) 86 ± 28 67 ± 37 69 ± 28 0.115
MR Rvol (ml) 49 ± 23 19 ± 13 9.5 ± 7.0 < 0.001 < 0.001 < 0.001 0.088
MR RF (%) 39 ± 13 21 ± 11 12 ± 8.0 < 0.001 0.001 < 0.001 0.022
RVEDVi (ml/m2) 92 ± 24 89 ± 18 91 ± 20 0.875
RVESVi (ml/m2) 44 ± 14 48 ± 13 45 ± 12 0.459
RVSVi (ml/m2) 49 ± 15 42 ± 8.6 46 ± 11 0.093
RVEF (%) 53 ± 8 47 ± 6.1 50 ± 5.7 0.011 0.01 0.698 0.224
TR Rvol (ml) 13 ± 17 11 ± 10 12 ± 9.0 0.628
TR RF (%) 15 ± 20 13 ± 11 13 ± 8.8 0.809
RAAi (cm2/m2) 14 ± 3 15 ± 3.6 14 ± 3.6 0.511
Native T1 (ms)* 1012 ± 36 1044 ± 43 1042 ± 37 0.042 0.084 0.068 1
ECV (%)* 27.8 ± 2.2 27.4 ± 3.6 27.0 ± 2.9 0.888
LGE presence** 7 (39%) 14(52%) 11 (55%) 0.634
 Non-ischaemic 5 (28%) 11(41%) 10 (50%) 0.698
 Ischaemic 2 (11%) 3 (11%) 1 (5%)
LGE (%)** 1.7 ± 2.7 4.3 ± 4.9 3.2 ± 3.7 0.242
LGE (g)** 1.9 ± 3.0 4.0 ± 4.3 3.0 ± 3.5 0.291

*Analysis performed on patients with paired baseline/follow-up data (control, n = 16; repair, n = 23; replace, n = 20). **Analysis performed on patients with paired baseline/follow-up data (control, n = 18; repair, n = 27; replace, n = 20). Abbreviations as in Tables 1 and 2