Table 5.
Multiple linear regression analysis of patient comorbidities and demographics impacting postoperative and pre/post-change (Δ) KOOS, JR scores
| Baseline variable | Postoperative KOOS, JR estimate effect | Δ KOOS, JR estimate effect | ||
|---|---|---|---|---|
| Estimate [95% CI] | P-value | Estimate [95% CI] | P-value | |
| Age (years) | 0.2 [0.1: 0.2] | < 0.001 | − 0.1 [− 0.2: 0.0] | 0.146 |
| Female | − 0.6 [− 1.9: 0.8] | 0.420 | 2.8 [1.0: 4.7] | 0.003 |
| BMI 18.5–25 kg/m2 (reference) | 1.0 | 1.0 | ||
| BMI 25.01–30 kg/m2 | − 2.2 [− 4.4: − 0.1] | 0.045 | 0.8 [− 2.2: 3.8] | 0.621 |
| BMI 30.01–40 kg/m2 | − 2.3 [− 4.: − 0.2] | 0.034 | 3.6 [0.8: 6.5] | 0.014 |
| BMI > 40 kg/m2 | − 1.9 [− 4.7: 0.8] | 0.163 | 8.0 [4.3: 11.7] | < 0.001 |
| White (reference) | 1.0 | 1.0 | ||
| African-American (Black) | − 4.9 [− 6.7: − 3.0] | < 0.001 | − 1.3 [− 3.8: 1.2] | 0.323 |
| Asian | − 0.4 [− 3.4: 2.7] | 0.803 | 2.2 [− 2.1: 6.4] | 0.326 |
| Other Race | − 3.2 [− 5.0: − 1.4] | < 0.001 | 0.8 [− 1.7: 3.2] | 0.537 |
| Myocardial Infarction | 0.9 [− 3.4: 5.2] | 0.683 | 0.3 [− 5.7: 6.3] | 0.919 |
| Cerebrovascular disease | − 2.9 [− 5.3: − 0.5] | 0.018 | − 2.1 [− 5.5: 1.2] | 0.209 |
| Chronic Pulmonary Disease | − 2.0 [− 3.7: − 0.3] | 0.024 | 2.5 [0.1: 4.8] | 0.045 |
| Mild Liver Disease | − 0.1 [− 3.1: 2.9] | 0.950 | 1.9 [− 2.4: 6.2] | 0.388 |
| DM without chronic complications | − 1.4 [− 3.1: 0.4] | 0.128 | 0.0 [− 2.3: 2.3] | 0.996 |
| DM with chronic complications | − 3.9 [− 7.8: 0.1] | 0.053 | − 4.5 [− 10.0: 1.0] | 0.110 |
| Malignancy lymphoma leukemia | − 1.7 [− 3.7: 0.4] | 0.107 | − 2.5 [− 5.3: 0.2] | 0.073 |
| Metastatic solid tumor | 1.8 [− 1.5: 5.1] | 0.293 | 2.9 [− 1.7: 7.4] | 0.210 |
Bold indicates statistical significance
BMI body mass index, KOOS, JR knee injury and osteoarthritis, joint replacement, CI confidence interval, DM diabetes mellitus