Table 6.
Multiple linear regression analysis of patient comorbidities and demographics impacting postoperative and pre/post-change (Δ) PROMIS-PH scores
| Baseline variable | Postoperative PROMIS GH estimate effect | Δ PROMIS GH estimate effect | ||
|---|---|---|---|---|
| Estimate [95% CI] | P-value | Estimate [95% CI] | P-value | |
| Age (years) | 0.1 [0.01: 0.1] | 0.009 | 0.01 [− 0.03: 0.05] | 0.562 |
| Female | − 1.8 [− 2.5: −1.1] | < 0.001 | 0.7 [− 0.03: 1.5] | 0.061 |
| BMI 18.5–25 kg/m2 (reference) | 1.0 | 1.0 | ||
| BMI 25.01–30 kg/m2 | − 0.6 [− 1.7: 0.5] | 0.293 | 0.6 [− 0.6: 1.8] | 0.341 |
| BMI 30.01–40 kg/m2 | − 1.5 [− 2.5: − 0.5] | 0.005 | 1.6 [0.4: 2.7] | 0.007 |
| BMI > 40 kg/m2 | − 2.1 [− 3.4: − 0.8] | 0.002 | 3.0 [1.6: 4.4] | < 0.001 |
| White (reference) | 1.0 | 1.0 | ||
| African-American (Black) | − 1.7 [− 2.6: − 0.8] | < 0.001 | − 0.1 [− 1.1: 0.8] | 0.800 |
| Asian | − 2.4 [− 3.9: − 0.8] | 0.003 | 1.0 [− 0.6: 2.6] | 0.211 |
| Other Race | − 3.0 [− 3.9: − 2.1] | < 0.001 | 1.2 [0.2: 2.2] | 0.018 |
| Myocardial Infarction | − 1.6 [− 3.8: 0.5] | 0.129 | − 0.3 [− 2.6: 2.1] | 0.829 |
| Cerebrovascular disease | − 0.4 [− 1.5: 0.8] | 0.542 | − 0.4 [− 1.7: 0.9] | 0.522 |
| Chronic Pulmonary Disease | − 1.0 [− 1.8: − 0.2] | 0.014 | − 0.4 [− 1.3: 0.5] | 0.375 |
| Mild Liver Disease | − 0.7 [− 2.2: 0.7] | 0.328 | − 0.3 [− 1.9: 1.2] | 0.682 |
| DM without chronic complications | − 1.6 [− 2.4: − 0.7] | < 0.001 | − 0.1 [− 1.0: 0.9] | 0.887 |
| DM with chronic complications | − 1.9 [− 3.7: 0.0] | 0.049 | − 0.8 [− 2.9: 1.3] | 0.464 |
| Malignancy lymphoma leukemia | 0.2 [− 0.8: 1.2] | 0.683 | 0.1 [− 1.0: 1.2] | 0.894 |
| Metastatic solid tumor | − 0.3 [− 2.0: 1.3] | 0.698 | − 1.1 [− 2.9: 0.6] | 0.211 |
Bold indicates statistical significance
BMI body mass index, PROMIS Patient-Reported Outcome Measurement Information System, Global PH Global Physical Health, DM diabetes mellitus, CI confidence interval