Table 2.
Demographic and clinical characteristics of the full HF cohort at index
| Unknown | HFrEF | HFpEF | Total | |
|---|---|---|---|---|
| n | 283,672 | 68,780 | 31,444 | 383,896 |
| Age at index (years) | ||||
| Mean (SD) | 76.1 (14.1) | 72.2 (13.7) | 71.7 (14.3) | 75.0 (14.2) |
| Sex | ||||
| Female | 139,125 (49.0) | 24,036 (34.9) | 16,287 (51.8) | 179,448 (46.7) |
| Male | 144,547 (51.0) | 44,744 (65.1) | 15,157 (48.2) | 204,448 (53.3) |
| Time since HF diagnosis (years) | ||||
| Mean (SD) | 2.3 (4.1) | 3.8 (4.7) | 2.2 (4.0) | 2.5 (4.3) |
| Number of HF hospitalisations (prior 12 months) | 30,010 (10.6) | 4,048 (5.9) | 811 (2.6) | 34,869 (9.1) |
| Ejection fraction | ||||
| Mean (SD) | - | 32.1 (8.9) | 54.7 (8.3) | 45.4 (14.0) |
| eGFR (ml/min/1.73m2) | ||||
| Mean (SD) | 62.7 (21.6) | 65.0 (21.5) | 67.2 (20.9) | 63.5 (21.6) |
| eGFR < 60 ml/min/1.73cm2 | 104,896 (37.0) | 24,432 (35.5) | 9,460 (30.1) | 138,788 (36.2) |
| Ever history of: | ||||
| Hypertension | 226,489 (79.8) | 51,939 (75.5) | 23,667 (75.3) | 302,095 (78.7) |
| Hyperlipidemia | 64,906 (22.9) | 17,423 (25.3) | 8,040 (25.6) | 90,369 (23.5) |
| T2D | 76,531 (27.0) | 17,839 (25.9) | 7,405 (23.5) | 101,775 (26.5) |
| IHD | 160,758 (56.7) | 46,655 (67.8) | 13,973 (44.4) | 221,386 (57.7) |
| MI | 69,680 (24.6) | 23,273 (33.8) | 4,190 (13.3) | 97,143 (25.3) |
| Coronary procedure | 94,732 (33.4) | 33,661 (48.9) | 9,317 (29.6) | 137,710 (35.9) |
| Other IHD | 146,871 (51.8) | 41,913 (60.9) | 12,437 (39.6) | 201,221 (52.4) |
| Stroke | 58,106 (20.5) | 11,956 (17.4) | 4,846 (15.4) | 74,908 (19.5) |
| PAD | 39,474 (13.9) | 8,775 (12.8) | 2,767 (8.8) | 51,016 (13.3) |
| COPD | 69,445 (24.5) | 13,683 (19.9) | 5,309 (16.9) | 88,437 (23.0) |
| Atrial fibrillation | 126,535 (44.6) | 30,405 (44.2) | 8,332 (26.5) | 165,272 (43.1) |
| CKD | 103,206 (36.4) | 23,051 (33.5) | 8,988 (28.6) | 135,245 (35.2) |
| Anaemia (in the previous year) | 42,165 (14.9) | 5,824 (8.5) | 2,783 (8.9) | 50,772 (13.2) |
Data are n (%) unless otherwise specified
CKD Chronic kidney disease, COPD Chronic obstructive pulmonary disease, eGFR Estimated glomerular filtration rate, HF Heart failure, HFpEF Heart failure with preserved ejection fraction, HFrEF Heart failure with reduced ejection fraction, IHD Ischaemic heart disease, MI Myocardial infarction, PAD Peripheral arterial disease, SD Standard deviation, T2D Type 2 diabetes