Table 2.

Treatment methods related to P.gingivalis.

Category	Therapeutic measures	Function	Reference
Periodontal initial therapy	scaling 、root planning、Laser Treatment	Improves insulin resistance and Blood glucose control, promotes wound healing	(Ni et al., 2018) (Chandra and Shashikumarr, 2019)
Medication	Plant polyphenol	Reduce the proinflammatory effect of LPS and increase insulin sensitivity	(Thouvenot et al., 2022) (Gao et al., 2014) (Furugen et al., 2013) (Everard et al., 2014) (Gurav and Jadhav, 2011) (Bedard and Krause, 2007)
Immunotherapy	P.g vaccine	Reduce inflammatory factor TNF- α And IL-6 expression	(Satoh and Ishihara, 2020) (Nishihara et al., 2009)