Table 1. DLS Analysis of the Hydrodynamic Size and Size Distribution of NPs in Freshly Diluted Comirnaty and Doxila.
NPs | Z-Ave | D(v) 10 | D(v) 50 | D(v) 90 | D(i) 10 | D(i) 50 | D(i) 90 | SPAN (i) | PDI | Zp |
---|---|---|---|---|---|---|---|---|---|---|
Comirnaty | 84.4 ± 0.3 | 40.6 ± 0.9 | 61.2 ± 0.9 | 109 ± 1.7 | 53 ± 0.3 | 88.7 ± 1 | 155.3 ± 0.6 | 1.1 | 0.20 | –8.6 ± 2.6 |
Doxil | 81.5 ± 0.4 | 48.7 ± 1.0 | 68.9 ± 1.0 | 105 ± 0.6 | 58 ± 0.9 | 84.5 ± 0.3 | 123 ± 0.6 | 0.8 | 0.06 | –31 ± 5.1 |
Entries are mean ± SD, n = 3 measurements. D(v) and D(i) refer to the distribution percentiles of the same sample based on intensity (Di) or volume (Dv) analysis. Span is defined as D90 – D10/D50 where D10, 50 and 90 are the percentiles under the size distribution curve; PDI, polydispersity index. Further details are described in the Methods section.