TABLE 2.
Demographics of study subjects.
| Characteristics at initial visit | Total (n = 794,448) | Dementia-free at follow-up (n = 744,924) | Incident dementia at follow-up (n = 49,524) |
| Sex | |||
| Male (%) | 364,765 | 349,785 (47.0%) | 14,980 (30.2%) |
| Female (%) | 429,683 | 395,139 (53.0%) | 34,544 (69.8%) |
| Age, year | |||
| Age groups, year | |||
| 45–50 | 219,972 | 219,956 (29.5%) | 16 (0.03%) |
| 50–55 | 161,729 | 161,517 (21.7%) | 212 (0.4%) |
| 55–60 | 114,461 | 113,702 (15.3%) | 759 (1.5%) |
| 60–65 | 91,648 | 90,156 (12.1%) | 1,492 (3.0%) |
| 65–70 | 79,279 | 75,859 (10.2%) | 3,420 (6.9%) |
| 70–75 | 56,999 | 49,522 (6.6%) | 7,477 (15.1%) |
| 75–80 | 35,753 | 24,036 (3.2%) | 11,717 (23.7%) |
| 80–85 | 21,063 | 8,881 (1.2%) | 12,182 (24.6%) |
| 85 + | 13,544 | 1,295 (0.2%) | 12,249 (24.7%) |
| Hypertension (%) | 257,273 | 229,407 (30.8%) | 27,866 (56.3%) |
| Diabetes mellitus (%) | 169,092 | 151,559 (20.3%) | 17,533 (35.4%) |
| Dyslipidemia (%) | 147,923 | 135,347 (18.2%) | 12,576 (25.4%) |
| Coronary heart disease (%) | 92,466 | 82,527 (11.1%) | 9,939 (20.1%) |
| Ischemic stroke (%) | 33,178 | 27,550 (3.7%) | 5,628 (11.4%) |
| Hemorrhagic stroke (%) | 4,419 | 3,802 (0.5%) | 617 (1.2%) |
| Depression (%) | 64,530 | 57,481 (7.7%) | 7,049 (14.2%) |
| Osteoporosis (%) | 114,386 | 100,467 (13.5%) | 13,919 (28.1%) |
| BMIa,b, kg/m2 | |||
| Underweight (%) | 7,891 | 7,099 (2.2%) | 792 (4.3%) |
| Normal (%) | 216,137 | 204,550 (62.3%) | 11,587 (62.5%) |
| Overweight (%) | 94,257 | 89,523 (27.3%) | 4,734 (25.5%) |
| Obesity (%) | 122,811 | 116,657 (35.5%) | 6,154 (33.2%) |
| Physical inactivitya (%) | 197,448 | 184,558 (56.2%) | 12,890 (69.6%) |
| Heavy alcohol consumptiona (%) | 28,176 | 27,252 (8.3%) | 924 (4.99%) |
| Smokinga (%) | 107,164 | 103,204 (31.4%) | 3,960 (21.4%) |
| Low socioeconomic status | 47,272 | 44,177 (13.5%) | 3,095 (16.7%) |
BMI, body mass index.
aTotal N = 346,839; dementia-free n = 328,306; dementia n = 18,533.
bBMI was classified as normal (18.5–22.9 kg/m2), underweight (<18.5 kg/m2), overweight (23–24.5 kg/m2), and obese (≥25 kg/m2).