Table 5.
Comparison of different studies calculated the CTV-PTV margin based on the measured intrafraction prostate motion data.
| Authors | Modality | Margin (mm) | Mean treatment time (mins) | No of patients | Coverage criteria | ||
|---|---|---|---|---|---|---|---|
| LR | AP | SI | |||||
| Polat et al (14) | CBCT | 6 | 6 | 6 | 16 | 21 | 90% PP-95%PD |
| Beltran et al (34) | Implanted fiducial and EPI images | 4.8 | 5.2 | 5.4 | 7 | 40 | 90% PP-95%PD |
| Kotte et al (35) | Implanted fiducial and EPI images | 2 | 2 | 2 | 5-7 | 427 | 90% PP-95%PD |
| Skarsgard et al (36) | Implanted fiducial and EPI images | 3.6 | 3.7 | 3.7 | Not specified | 72 | 95% probability of complete CTV coverage |
| Steiner et al (37) | Implanted fiducial and stereoscopic kV images | 3.7 | 3.6 | 2.6 | 9.7 | 9 | 90% PP-95%PD |
| 2.3 | 6.2 | 3.9 | 15.0 | 3 | |||
| Both et al (38) | Electromagnetic localization and tracking | 3 | 3 | 3 | 6 | 24 | CTV for 95% of treatment time |
| Wang et al (39) | Electromagnetic localization and tracking | 3 | 3 | 3 | 6 | 30 | Margin covering CTV for 95% of treatment time |
| Pang et al (40) | Clarity 4D TPUS | 1.02 | 2.65 | 2.41 | 8 | 55 | 90% PP-95%PD |
| 1.84 | 4.63 | 4.29 | 15 | ||||
| Franco et al (30) | Clarity 4D TPUS | 5 | 5 | 5 | 7 | 46 | 95% PP-99%PD |
4D TPUS- Four-dimensional transperineal Ultrasound.
90%PP-95%PD-90% of the patient population receiving 95% prescription dose.
95%PP-99%PD-95% of the patient population receiving 99% prescription dose.