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. 2023 Jul 24;11:e15734. doi: 10.7717/peerj.15734

Table 2. The general characteristics of the included studies.

Study, Year Country Study
type
Age
(years)
Gender
(female/ male)
Anesthesia
 technique
(C/I)
Number
of 
patients
(C/I)
Number of
 Successful
 anesthesia
(C/I)
Anesthetized tooth
 position
Outcomes
Al-Shayyab (2017) Jordan RCT
(split
mouth)
mean ±SD: 34.87 ± 14.93; range:13–65 23/32 intraligamentary anesthesia/
supraperiosteal anesthesia
55/55 39/49 Posterior maxillary permanent teeth VAS, success rate, VRS
Biocanin et al. (2013) Serbia RCT
(parallel)
mean ±SD: 27.8 ± 9.9; range: 24–31 28/32 intraligamentary anesthesia/
intraseptal anesthesia
30/30 21/27 Mandibular first premolars success rate, onset time, duration of anesthesia, the width of the anesthetic field
Brkovic et al. (2010) Serbia RCT
(split
mouth)
mean ±SD: 37.1 ± 12.3 19/16 intraligamentary anesthesia/
intraseptal anesthesia
35/35 32/31 Maxillary lateral incisors extraction VAS, success rate, onset time, duration of anesthesia
Jain & Nazar (2018) India RCT
(parallel)
range:18–40 NR intraligamentary anesthesia/
supraperiosteal anesthesia
15/15 15/15 Maxillary teeth VAS, success rate
Meechan & Ledvinka (2002) UK RCT
(split
mouth)
range: 21–24 NR intraligamentary anesthesia/
supraperiosteal anesthesia
12/12 0/10 Mandibular central incisors VAS, success rate
Ryalat et al. (2018) Jordan RCT
(split
mouth)
mean: 32.15; range: 11–65 11/29 intraligamentary anesthesia/
supraperiosteal anesthesia
40/40 34/25 Maxillary first molar teeth VAS, VRS, success rate
Subramaniam, Dhanraj & Jain (2018) India RCT
(parallel)
range: 25–40 4/8 intraligamentary anesthesia/
subperiosteal infiltration
6/6 6/6 NR VAS, success rate

Notes.

SD
standard deviation
C
control group
I
intervention group
NR
not reported
RCT
randomized controlled trial
VAS
visual analog scale