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. 2023 Jul 5;15(13):6264–6291. doi: 10.18632/aging.204850

Figure 2.

Figure 2

Significantly activated pathways in different molecular subtypes. (A) GSEA analysis results in the TCGA-LGG cohort. (B) Variation in the scores of 10 tumor abnormality-related pathways in various TCGA-LGG molecular subtypes in the **P < 0.01; ***P < 0.001; ****P < 0.0001. Abbreviations: ns: no significance; NES: normalized enrichment scores; ssGSEA: single-sample GSEA; GSEA: gene set enrichment analysis; TCGA: The Cancer Genome Atlas; LGG: low-grade glioma; TP53: tumor protein p53; PI3K: phosphatidylinositol 3-kinase; NRF1: nuclear respiratory factor-1; TGF-β: transforming growth factor-β.