Table 3.
Assessments of AMSTAR scores and GRADE classification.
| Outcome | Category | Author | Year | AMSTAR | GRADE |
|---|---|---|---|---|---|
| Non-cancer outcomes | |||||
| Significant associations | |||||
| Cardiovascular disease | Vitamin E supplements | Han | 2020 | 10 | Low |
| Parkinson's Disease | Dietary vitamin E | Talebi | 2022 | 8 | Very low |
| Depression | Dietary vitamin E | Lee | 2022 | 8 | Very low |
| Anxiety | Dietary vitamin E | Lee | 2022 | 8 | Very low |
| Age-related Cataract | Dietary vitamin E | Jiang | 2019 | 9 | Very low |
| Metabolic Syndrome | Dietary vitamin E | Zhang | 2021 | 9 | Very low |
| Fracture | Dietary vitamin E | Zhou | 2020 | 9 | Low |
| Non-significant associations | |||||
| Stroke | Vitamin E supplements | Loh | 2021 | 9 | Moderate |
| Parkinson's Disease | Dietary vitamin E | Talebi | 2022 | 8 | Very low |
| Alzheimer's Disease | Vitamin E supplements | Wang | 2021 | 9 | Very low |
| Obesity | Vitamin E supplements | Mohammad | 2021 | 10 | Moderate |
| Glaucoma | Dietary vitamin E | Han | 2022 | 7 | Very low |
| Age-related Cataract | Dietary vitamin E | Jiang | 2019 | 9 | Moderate |
| All-Cause Mortality | Dietary vitamin E | Jayedi | 2018 | 7 | Low |
| Cancer outcomes | |||||
| Significant associations | |||||
| Breast Cancer | Total intake vitamin E | Fulan | 2011 | 10 | Low |
| Breast Cancer | Dietary vitamin E | Fulan | 2011 | 10 | Low |
| Lung Cancer | Dietary vitamin E | Zhu | 2017 | 7 | Low |
| Esophageal Cancer | Dietary vitamin E | Cui | 2018 | 7 | Very low |
| Gastric Cancer | Dietary vitamin E | Kong | 2014 | 8 | Low |
| Pancreatic Cancer | Dietary vitamin E | Chen | 2016 | 9 | Low |
| Kidney Cancer | Dietary vitamin E | Shen | 2015 | 8 | Low |
| Bladder Cancer | Dietary vitamin E | Lin | 2019 | 8 | Low |
| Cervical Neoplasm | Total intake vitamin E | Hu | 2017 | 8 | Very low |
| Non-significant associations | |||||
| Glioma | Dietary vitamin E | Qin | 2014 | 9 | Very low |
| Thyroid Cancer | Dietary vitamin E | Zhang | 2013 | 6 | Very low |
| Breast Cancer | Combined intake vitamin E | Fulan | 2011 | 10 | Low |
| Breast Cancer | Combined intake vitamin E | Fulan | 2011 | 10 | Low |
| Colorectal Cancer | Dietary vitamin E | Liu | 2015 | 9 | Very low |
| Kidney Cancer | Dietary vitamin E | Shen | 2015 | 8 | Low |
| Endometrial Cancer | Dietary vitamin E | Elisa | 2008 | 6 | Low |
| Ovarian Cancer | Total intake vitamin E | Leng | 2019 | 9 | Very low |
| NHL | Total intake vitamin E | Psaltopoulou | 2018 | 5 | Very low |
| Total Cancer | Dietary vitamin E | Aune | 2018 | 7 | Low |
| Cancer Mortality | Dietary vitamin E | Schwingshackl | 2017 | 8 | Very low |
AMSTAR, a measurement tool to assess systematic reviews; GRADE, Grading of Recommendations Assessment, Development, and Evaluation; NHL, non-Hodgkin lymphoma.