Table 4.

Univariate and multivariate Cox regression analyses of risk factors for progression-free survival in Cohort 5.

	Univariate HR (95% CI)	P value	Multivariate HR (95% CI)	P value
AFP, ng/ml
≤ 400	1.0
> 400	2.71 (1.69-4.37)	<0.001	2.11 (1.29 - 3.48)	0.003
Age	0.98 (0.96-1)	0.040
ALBI grade
1	1.0
2	0.96 (0.59-1.56)	0.868
3	1.68 (0.84-3.39)	0.145
Child-Pugh grade
A	1.0
B+C	1.09 (0.67-1.78)	0.728
Cirrhosis
Absent	1.0
Present	1.56 (0.88-2.77)	0.128
CRP	1.01 (1-1.01)	0.001	1.01 (1 - 1.01)	0.048
ECOG PS
0	1.0
1 + 2	0.94 (0.61-1.44)	0.766
Embolus
Absent	1.0
Present	0.92 (0.6-1.42)	0.717
Aetiology
HBV	1.0
HCV	1.33 (0.18-9.57)	0.779
Others	1.11 (0.45-2.75)	0.817
NLR	1.15 (1.06-1.25)	0.001
RNETS	3.4 (1.86-6.2)	<0.001	2.49 (1.29 - 4.81)	0.007
Gender
Female	1.0
Male	0.84 (0.43-1.62)	0.599
Tumor number
≤ 3	1.0
> 3	1.02 (0.65-1.59)	0.936
Tumor size, cm	1.04 (0.99-1.09)	0.125