. 2023 Jul 13;4:1213750. doi: 10.3389/fpain.2023.1213750

Table 4.

Results from the multinomial regression for the association between SEDs and CP interference and the number of pain sites.

No pain vs.	Multinomial regression
	Pain interference		Number of pain locations
	Low-interference pain	High-interference pain	0–2	3+
	Odds ratio (95%CI)		Odds ratio (95% CI)
Main analysis
Period-specific SED
SEDs at childhood^a	0.94 (0.83–1.07)	1.11 (0.94–1.31)	0.92 (0.81–1.04)	1.14 (0.97–1.34)
SEDs at MIDUS 1^b	1.03 (0.94–1.14)	1.03 (0.90–1.18)	0.99 (0.89–1.10)	1.11 (0.98–1.26)
SEDs at MIDUS 2^c	1.05 (0.95–1.16)	1.15 (1.01–1.32)^*	1.09 (0.99–1.21)	1.05 (0.92–1.20)
Lifetime disadvantages^c
Total SEDs	1.01 (0.97–1.06)	1.04 (0.97–1.12)	1.01 (0.96–1.06)	1.05 (0.98–1.12)
SED trajectory—class (k = 3, reference = always low)^a,^c
Middle to high	1.46 (0.78–2.7)	3.22 (1.35–7.71)^**	1.37 (0.74–2.56)	3.06 (1.28–7.32)^*
High to low	0.89 (0.55–1.43)	1.69 (0.81–3.52)	0.85 (0.52–1.39)	1.77 (0.87–3.6)

^{^a}

Adjusted for gender, age at MIDUS 1, race/ethnicity, whether living with smoker/alcoholic during childhood, whether living with biological parents during childhood, parental health, and emotional/physical abuse from mothers/fathers.

^{^b}

Adjusted for gender, age at MIDUS 1, race/ethnicity, marital status at MIDUS 1, number of chronic conditions, support from family/friends at MIDUS 1, personal mastery at MIDUS 1, smoking behavior at MIDUS 1, drinking behavior at MIDUS 1, and activity at MIDUS 1.

^{^c}

Adjusted for gender, age at MIDUS 2, race/ethnicity, marital status at MIDUS 2, number of chronic conditions, support from family/friends at MIDUS 2, personal mastery at MIDUS 2, smoking behavior at MIDUS 2, drinking behavior at MIDUS 2, and activity at MIDUS 2.

Significant at the 5% level.

^**

Significant at the 1% level.

^***

Significant at the 0.1% level.

The bold values denote statistically significant results.