. 2023 Jul 13;4:1213750. doi: 10.3389/fpain.2023.1213750

Table 5.

Results from the negative binomial regression for the association between SEDs and AL.

	Negative binomial regression
	AL index quartile-based
	IRR (95%CI)
Main analysis
Period-specific SED
SEDs at childhood^a	1.04 (1.01–1.07)^**
SEDs at MIDUS 1^b	1.03 (1.01–1.06)^**
SEDs at MIDUS 2^c	1.03 (1.01–1.05)^**
Lifetime disadvantages^c
Total SEDs	1.02 (1.01–1.03)^***
SED trajectory—class (k = 3, reference = always low)^a,^c
Middle to high	1.19 (1.05–1.36)^**
High to low	1.11 (1.01–1.22)^*

^{^a}

Adjusted for gender, age at MIDUS 1, race/ethnicity, whether living with smoker/alcoholic during childhood, whether living with biological parents during childhood, parental health, and emotional/physical abuse from mothers/fathers.

^{^b}

Adjusted for gender, age at MIDUS 1, race/ethnicity, marital status at MIDUS 1, number of chronic conditions, support from family/friends at MIDUS 1, personal mastery at MIDUS 1, smoking behavior at MIDUS 1, drinking behavior at MIDUS 1, and activity at MIDUS 1.

^{^c}

Adjusted for gender, age at MIDUS 2, race/ethnicity, marital status at MIDUS 2, number of chronic conditions, support from family/friends at MIDUS 2, personal mastery at MIDUS 2, smoking behavior at MIDUS 2, drinking behavior at MIDUS 2, and activity at MIDUS 2.

Significant at the 5% level.

^**

Significant at the 1% level.

^***

Significant at the 0.1% level.

The bold values denote statistically significant results.