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. 2023 Jul 7;17(5):465–475. doi: 10.1049/nbt2.12144

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© 2023 The Authors. IET Nanobiotechnology published by John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Chaetocin mediated the decrease of CD47 expression and enhancement of phagocytosis of macrophages in A549 cells. (a) The expression of CD47 was recorded by qPCR on A549 cells after chaetocin at various time intervals (b) Expression of total CD47 protein at different periods by western blot technique. (c) Cytotoxicity of chaetocin against A549 cells at different concentrations using CCK8 cell viability assay (d) Cytotoxicity of chaetocin against PBMC cells using MTT assay *p < 0.05 indicates the statistical significance between control and treated groups.